[HTML][HTML] Endometrial stem/progenitor cells–their role in endometrial repair and regeneration

FL Cousins, CE Filby, CE Gargett - Frontiers in Reproductive Health, 2022 - frontiersin.org
The human endometrium is a remarkable tissue, undergoing approximately 450 cycles of
proliferation, differentiation, shedding (menstruation), repair and regeneration over a …

Urolithins: The colon microbiota metabolites as endocrine modulators: Prospects and perspectives

R Vini, JM Azeez, V Remadevi, TR Susmi… - Frontiers in …, 2022 - frontiersin.org
Selective estrogen receptor modulators (SERMs) have been used in hormone related
disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the …

[HTML][HTML] In vitro modeling of endometriosis and endometriotic microenvironment–Challenges and recent advances

A Gołąbek-Grenda, A Olejnik - Cellular signalling, 2022 - Elsevier
Endometriosis is a chronic condition with high prevalence in reproductive age women,
defined as the growth of endometrial tissue outside the uterine cavity, most commonly on the …

Gut bacterial metabolite urolithin a decreases actin polymerization and migration in cancer cells

M Alauddin, T Okumura, J Rajaxavier… - Molecular nutrition & …, 2020 - Wiley Online Library
Scope Urolithin A (UA) is a gut‐derived bacterial metabolite from ellagic acid found in
pomegranates, berries, and nuts can downregulate cell proliferation and migration. Cell …

Effect and mechanisms of kaempferol against endometriosis based on network pharmacology and in vitro experiments

J Zhao, J Wang, J Liu, S Li, P Liu, X Zhang - … Complementary Medicine and …, 2022 - Springer
Endometriosis is a common gynecological disease, and its underlying mechanisms remain
elusive. Patients are at a higher risk of recurrence after surgery or drug withdrawal. In this …

Impact of Musashi-1 and Musashi-2 double knockdown on notch signaling and the pathogenesis of endometriosis

T Strauß, B Greve, M Gabriel, N Achmad… - International Journal of …, 2022 - mdpi.com
The stem cell marker and RNA-binding protein Musashi-1 is overexpressed in
endometriosis. Musashi-1-siRNA knockdown in Ishikawa cells altered the expression of …

MCP-1 exerts the inflammatory response via ILK activation during endometriosis pathogenesis

UK Soni, R Tripathi, RK Jha - Life Sciences, 2024 - Elsevier
Aims MCP-1 has been shown to be elevated in endometriosis. ILK functions in several
cellular events and interacts with MCP-1-signaling. In the current study, we evaluated the …

[HTML][HTML] Bioengineering approaches for the endometrial research and application

W Dai, J Liang, R Guo, Z Zhao, Z Na, D Xu, D Li - Materials Today Bio, 2024 - Elsevier
The endometrium undergoes a series of precise monthly changes under the regulation of
dynamic levels of ovarian hormones that are characterized by repeated shedding and …

Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis

J Li, Y He, Y Qu, C Ren, X Wang, Y Cheng… - Frontiers in …, 2023 - frontiersin.org
Background Endometriosis (EM) is a benign, multifactorial, immune-mediated inflammatory
disease that is characterized by persistent activation of the NF‐κB signaling pathway and …

Resveratrol impairs cellular mechanisms associated with the pathogenesis of endometriosis

D Madanes, G Meresman, SA Valla, N Hassan… - Reproductive …, 2022 - Elsevier
Research question Does resveratrol exert a potent inhibitory effect on the development of
endometriosis by interfering with some pivotal processes? Design In-vitro cultures of primary …