Human sperm as an in vitro model to assess the efficacy of antioxidant supplements during sperm handling: A narrative review

E Moretti, C Signorini, R Corsaro, M Giamalidi… - Antioxidants, 2023 - mdpi.com
Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due
to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction …

Oxidative Stress Biomarkers in Male Infertility: Established Methodologies and Future Perspectives

F Mottola, I Palmieri, M Carannante, A Barretta… - Genes, 2024 - mdpi.com
Male fertility can be affected by oxidative stress (OS), which occurs when an imbalance
between the production of reactive oxygen species (ROS) and the body's ability to neutralize …

Polymorphic rearrangements of human chromosome 9 and male infertility: new evidence and impact on spermatogenesis

F Mottola, M Santonastaso, V Ronga, R Finelli, L Rocco - Biomolecules, 2023 - mdpi.com
Chromosomal polymorphisms are structural variations in chromosomes that define the
genomic variance of a species. These alterations are recurrent in the general population …

[HTML][HTML] Crosstalk Between Oxidative Stress and Epigenetics: Unveiling New Biomarkers in Human Infertility

S Dutta, P Sengupta, F Mottola, S Das, A Hussain… - Cells, 2024 - mdpi.com
The correlation between epigenetic alterations and the pathophysiology of human infertility
is progressively being elucidated with the discovery of an increasing number of target genes …

Endocrine-disrupting chemicals (EDCs) and male infertility

L Rocco, D Durairajanayagam, F Mottola - Current and Future Advances in …, 2024 - Springer
Exposure to environmental contaminants has been an important cause of the decline in
male fertility in the last 20 years. The most serious threat is represented by the release into …

Protective Effects of Anthocyanin and α-Tocopherol Against Titanium Dioxide Nanoparticle-Induced DNA Damage in Human Sperm Cells

M Santonastaso, F Mottola, C Iovine, V Genualdo… - Exposure and …, 2024 - Springer
The male reproductive system is known for its high complexity and sensitivity, particularly
concerning environmental stressors. Titanium dioxide nanoparticles (TiO2-NPs) could alter …

[HTML][HTML] Reproductive cytotoxic and genotoxic impact of polystyrene microplastic on Paracentrotus lividus spermatozoa

F Mottola, M Carannante, A Barretta, I Palmieri… - Current Research in …, 2024 - Elsevier
In recent decades, industrialization, intensive agriculture, and urban development have
severely impacted marine environments, compromising the health of aquatic and terrestrial …

Molecular Research on Reproductive Toxicity

R Scudiero - International Journal of Molecular Sciences, 2023 - mdpi.com
Fertility rates in animals have shown a progressive decrease in recent decades, and
reproductive toxicity is considered an important regulatory endpoint in health hazard …

[HTML][HTML] Methanolic pomegranate dried peel extract improves cryopreserved semen quality and antioxidant capacity of rams

AM Aboelmaaty, MS Kotp, AM Fadl… - Asian Pacific Journal …, 2023 - journals.lww.com
Objective: To select the appropriate concentrations of methanolic pomegranate extract
supplemented in rams' semen extender for obtaining the best-cryopreserved semen quality …

不同浓度鞣花酸对猪精液常温保存效果的影响

屈先先, 舒亮, 孙小晶, 刘梅, 高凤仙, 杨泰 - 中国畜牧兽医, 2024 - chvm.net
[目的] 研究鞣花酸(ellagicacid, EA) 对公猪精液常温保存过程中精子质量及抗氧化性能的影响,
以期为鞣花酸在精液保存中的推广应用提供理论依据.[方法] 试验采集4 头2~ 3 …