Use of Oleuropein and Hydroxytyrosol for Cancer Prevention and Treatment: Considerations about How Bioavailability and Metabolism Impact Their Adoption in …

F Gervasi, F Pojero - Biomedicines, 2024 - mdpi.com
The fact that the Mediterranean diet could represent a source of natural compounds with
cancer-preventive and therapeutic activity has been the object of great interest, especially …

Anti-Inflammatory effects of olive leaf extract and its bioactive compounds oleacin and oleuropein-aglycone on senescent endothelial and small airway epithelial cells

A Silvestrini, C Giordani, S Bonacci, A Giuliani… - Antioxidants, 2023 - mdpi.com
Olive tree by-products have been deeply studied as an invaluable source of bioactive
compounds. Several in vitro and in vivo studies showed that olive leaf extract (OLE) has anti …

A Narrative Review of Metabolomic Insights into Olive Oil's Nutritional Value

M Gonçalves, M Rodríguez-Pérez, A Calabrò… - Applied Sciences, 2024 - mdpi.com
This review explores the critical role of advanced metabolomic methodologies in interpreting
the complex relationship between the bioactive compounds in olive oil and their health …

Olive Oil Waste as a Source of Functional Food Ingredients: Assessing Polyphenolic Content and Antioxidant Activity in Olive Leaves

CL Ronca, SS Marques, A Ritieni, R Giménez-Martínez… - Foods, 2024 - mdpi.com
Around two million tons of olive oil are produced in Europe annually, with Portugal being
among the top five European olive oil-producing countries. Olive oil production results in a …

Comparative Study of the Efficacy of EHO-85, a Hydrogel Containing Olive Tree (Olea europaea) Leaf Extract, in Skin Wound Healing

B Torrecillas-Baena, M Camacho-Cardenosa… - International Journal of …, 2023 - mdpi.com
Olive tree (Olea europaea) leaf extract (OELE) has important antioxidant and anti-
inflammatory properties, supporting its use in human clinical practice. We recently designed …

Anti-inflammatory effects of nutritionally relevant concentrations of oleuropein and hydroxytyrosol on peripheral blood mononuclear cells: an age-related analysis

F Pojero, F Gervasi, SD Fiore, A Aiello… - International Journal of …, 2023 - mdpi.com
Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The
Mediterranean diet is a non-invasive intervention to improve the chronic low-grade …

Oleuropein activates autophagy to circumvent anti-plasmodial defense

P Sharma, N Tandel, R Kumar, S Negi, P Sharma… - Iscience, 2024 - cell.com
Antimalarial drug resistance and unavailability of effective vaccine warrant for newer drugs
and drug targets. Hence, anti-inflammatory activity of phyto-compound (oleuropein; OLP) …

A Comparative Study of Oleuropein Extraction from Wild Olive Leaves (Olea europea subsp. oleaster, Hoffmanns. & Link), Its Gastrointestinal Stability, and Biological …

B Soldo, T Bilušić, J Giacometti, I Ljubenkov… - Applied Sciences, 2024 - mdpi.com
Olive leaves are the richest source of phenolic compounds, particularly oleuropein, which
has many beneficial effects on human health. This study compares the effect of three …

[HTML][HTML] IL-17A Drives Oxidative Stress and Cell Growth in A549 Lung Epithelial Cells: Potential Protective Action of Oleuropein

AM Montalbano, C Di Sano, GD Albano, M Gjomarkaj… - Nutrients, 2024 - mdpi.com
IL-17A drives inflammation and oxidative stress, affecting the progression of chronic lung
diseases (asthma, chronic obstructive pulmonary disease (COPD), lung cancer, and cystic …

Oleuropein Stimulates Migration of Human Trophoblast Cells and Expression of Invasion-Associated Markers

A Pirković, M Jovanović Krivokuća, A Vilotić… - International Journal of …, 2023 - mdpi.com
Successful pregnancy establishment requires highly synchronized cross talk between the
invasive trophoblast cells and the receptive maternal endometrium. Any disturbances in this …