Need for clarity and context in case reports on kratom use, assessment, and intervention

KE Smith, KE Dunn, DH Epstein… - Substance …, 2022 - journals.sagepub.com
This Letter to the Editor is a response to Broyan and colleagues who recently published a
Case Report presenting data on 28 patients in the United States who identified kratom as …

Pharmacokinetics and safety of mitragynine in beagle dogs

EA Maxwell, TI King, SH Kamble, KSR Raju… - Planta …, 2020 - thieme-connect.com
Mitragynine is the most abundant psychoactive alkaloid derived from the leaves of Mitragyna
speciosa (kratom), a tropical plant indigenous to regions of Southeast Asia. Mitragynine …

Kratom (Mitragyna speciosa): worldwide issues

S Ramanathan, CR McCurdy - Current Opinion in Psychiatry, 2020 - journals.lww.com
To inform readers about the increasingly popular Western dietary supplement, kratom
(Mitragyna speciosa) and how the products are available in the Western world compared …

How essential is kratom availability and use during COVID-19? Use pattern analysis based on survey and social media data

O Grundmann, CA Veltri, D Morcos… - Substance …, 2022 - journals.sagepub.com
Background: Kratom, a tree native to Southeast Asia, is increasingly used in Western
countries for self-treatment of pain, psychiatric disorders, and mitigation of withdrawal …

Associations of lifetime nonmedical opioid, methamphetamine, and kratom use within a nationally representative US sample

KE Smith, JM Rogers, JC Strickland - Journal of psychoactive …, 2022 - Taylor & Francis
Co-use of non-medical opioids (NMO) and methamphetamine is increasing. So too is the
use of the psychoactive botanical “kratom,” including among people with NMO and …

Ameliorative effects of alkaloid extract from Mitragyna speciosa (Korth.) Havil. Leaves on methamphetamine conditioned place preference in mice

J Nukitram, D Cheaha, N Sengnon… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Mitragyna speciosa (Korth.) Havil., popularly
known as Kratom (KT), is a medicinal plant used for pain suppression in Southeast Asia. It …

Cannabinoid mechanisms contribute to the therapeutic efficacy of the kratom alkaloid mitragynine against neuropathic, but not inflammatory pain

DJ Farkas, S Inan, LN Heydari, CT Johnson, P Zhao… - Life Sciences, 2023 - Elsevier
Aims Mitragynine (MG) is an alkaloid found in Mitragyna speciosa (kratom), a plant used to
self-treat symptoms of opioid withdrawal and pain. Kratom products are commonly used in …

[HTML][HTML] Kratom alkaloid mitragynine: Inhibition of chemotherapy-induced peripheral neuropathy in mice is dependent on sex and active adrenergic and opioid …

DJ Farkas, JD Foss, SJ Ward, SM Rawls - IBRO Neuroscience Reports, 2022 - Elsevier
Mitragynine (MG) is an alkaloid found in Mitragyna speciosa (kratom) that is used as an
herbal remedy for pain relief and opioid withdrawal. MG acts at μ-opioid and α-adrenergic …

Kratom: A systematic review of toxicological issues

S Kerrigan, S Basiliere - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Kratom is a botanical substance derived from the leaves of Mitragyna speciosa. Although
kratom has been used traditionally in Southeast Asia for over a century, recreational use and …

Correlations of kratom (Mitragyna speciosa Korth.) use behavior and psychiatric conditions from a cross-sectional survey.

O Grundmann, CA Veltri, S Morcos… - Experimental and …, 2023 - psycnet.apa.org
Abstract Kratom (Mitragyna speciosa Korth.) use has increased substantially over the past
decade outside of its indigenous regions, especially for the self-treatment of psychiatric …