[HTML][HTML] New Potentiality of Bioactive Substances: Regulating the NLRP3 Inflammasome in Autoimmune Diseases

B Chen, Y Wang, G Chen - Nutrients, 2023 - mdpi.com
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an
essential component of the human innate immune system, and is closely associated with …

[HTML][HTML] Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

M Li, F Tian, J Guo, X Li, L Ma, M Jiang… - Frontiers in …, 2023 - frontiersin.org
Arthritis is a common degenerative disease of joints, which has become a public health
problem affecting human health, but its pathogenesis is complex and cannot be eradicated …

[HTML][HTML] Senkyunolide I ameliorates thoracic aortic aneurysm and dissection in mice via inhibiting the oxidative stress and apoptosis of endothelial cells

K Zhao, H Zhu, X He, P Du, T Liang, Y Sun… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Background Thoracic aortic aneurysm and aortic dissection (TAAD) is one of the most fatal
cardiovascular diseases. Senkyunolide I (SEI) is a component of traditional Chinese …

[HTML][HTML] NLRP3 inflammasome and its role in autoimmune diseases: A promising therapeutic target

W Ren, Y Sun, L Zhao, X Shi - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines IL-1β and …

A novel pharmaceutical preparation of Tripterygium wilfordii Hook. f. regulates macrophage polarization to alleviate inflammation in rheumatoid arthritis

L Wan, J Liu, C Huang, K Wang… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To validate the enhanced therapeutic effect of Tripterygium wilfordii Hook.
f.(TWHF) in the treatment of rheumatoid arthritis (RA) by restoring homeostasis of M1/M2 …

Mechanisms of NLRP3 inflammasome in rheumatoid arthritis and osteoarthritis and the effects of traditional Chinese medicine

R Zhang, L Han, W Lin, X Ba, J Yan, T Li, Y Yang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance It has been widely reported that various anti-rheumatic
traditional Chinese medicines (TCMs) ameliorate rheumatoid arthritis (RA) and osteoarthritis …

Locally immunological effects of honey applications in patients with rheumatoid arthritis

ZF Saeed, BA Kadhim, MA Alsaadawi… - AIP Conference …, 2024 - pubs.aip.org
Rheumatoid arthritis is a condition that causes joint pain, swelling, and stiffness, it is
considered to be an autoimmune disease and it is widely spread in Al Samawah city in Iraq …

Amarogentin Alleviates Osteoarthritis by Regulating Chondrocyte Proliferation and Autophagy.

W Luo, D Zhu, Y Yang, H Li, J Jin… - Current Topics in …, 2023 - search.ebscohost.com
Although amarogentin has been shown to play an amelioration role in several disease
states, its role in osteoarthritis progression remains unexplored. To this end, we have …