Current approaches and developments in transcript profiling of the human placenta
BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …
molecular marks of rapid development and exposures in utero. The placenta is routinely …
TXNDC5, a newly discovered disulfide isomerase with a key role in cell physiology and pathology
E Horna-Terrón, A Pradilla-Dieste… - International journal of …, 2014 - mdpi.com
Thioredoxin domain-containing 5 (TXNDC5) is a member of the protein disulfide isomerase
family, acting as a chaperone of endoplasmic reticulum under not fully characterized …
family, acting as a chaperone of endoplasmic reticulum under not fully characterized …
Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network
Background Intrauterine metal exposures and aberrations in placental processes are known
contributors to being born small for gestational age (SGA). However, studies to date have …
contributors to being born small for gestational age (SGA). However, studies to date have …
Biomarkers for macrosomia prediction in pregnancies affected by diabetes
S Nahavandi, J Seah, A Shub, C Houlihan… - Frontiers in …, 2018 - frontiersin.org
Large birthweight, or macrosomia, is one of the commonest complications for pregnancies
affected by diabetes. As macrosomia is associated with an increased risk of a number of …
affected by diabetes. As macrosomia is associated with an increased risk of a number of …
Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension
K Grabowski, L Herlan, A Witten, F Qadri… - Hypertension …, 2022 - nature.com
Abstract Treatment of hypertension-mediated cardiac damage with left ventricular (LV)
hypertrophy (LVH) and heart failure remains challenging. To identify novel targets, we …
hypertrophy (LVH) and heart failure remains challenging. To identify novel targets, we …
A co-expression analysis of the placental transcriptome in association with maternal pre-pregnancy BMI and newborn birth weight
Maternal body mass index (BMI) before pregnancy is known to affect both fetal growth and
later-life health of the newborn, yet the implicated molecular mechanisms remain largely …
later-life health of the newborn, yet the implicated molecular mechanisms remain largely …
[HTML][HTML] TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration, vasculogenic mimicry and angiogenesis by down-regulating SERPINF1 and …
B Xu, J Li, X Liu, C Li, X Chang - Oncotarget, 2017 - ncbi.nlm.nih.gov
TXNDC5 (thioredoxin domain-containing protein 5) catalyzes disulfide bond formation,
isomerization and reduction. Studies have reported that TXNDC5 expression is increased in …
isomerization and reduction. Studies have reported that TXNDC5 expression is increased in …
[HTML][HTML] Epitranscriptomic profiling in human placenta: N6‐methyladenosine modification at the 5′‐untranslated region is related to fetal growth and preeclampsia
K Taniguchi, T Kawai, J Kitawaki, J Tomikawa… - The FASEB …, 2020 - ncbi.nlm.nih.gov
Intracellular mRNA levels are not always proportional to their respective protein levels,
especially in the placenta. This discrepancy may be attributed to various factors including …
especially in the placenta. This discrepancy may be attributed to various factors including …
[HTML][HTML] The expression profile of circRNA and its potential regulatory targets in the placentas of severe pre-eclampsia
Y Ou, M Liu, L Zhu, K Deng, M Chen, H Chen… - Taiwanese Journal of …, 2019 - Elsevier
Objective To determine the expression profiles of circular RNAs (circRNAs) of women with
severe pre-eclampsia (sPE group) versus normal pregnancies (normal control group) …
severe pre-eclampsia (sPE group) versus normal pregnancies (normal control group) …
Overexpression of CPXM2 predicts an unfavorable prognosis and promotes the proliferation and migration of gastric cancer
G Niu, Y Yang, J Ren, T Song, Z Hu… - Oncology …, 2019 - spandidos-publications.com
Carboxypeptidase X, M14 family member 2 (CPXM2), has been associated with several
human disorders such as developmental diseases. However, whether CPXM2 is involved in …
human disorders such as developmental diseases. However, whether CPXM2 is involved in …