Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

[HTML][HTML] Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

[HTML][HTML] mRNA-based therapeutics—developing a new class of drugs

U Sahin, K Karikó, Ö Türeci - Nature reviews Drug discovery, 2014 - nature.com
In vitro transcribed (IVT) mRNA has recently come into focus as a potential new drug class to
deliver genetic information. Such synthetic mRNA can be engineered to transiently express …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Treating metastatic cancer with nanotechnology

A Schroeder, DA Heller, MM Winslow… - Nature Reviews …, 2012 - nature.com
Metastasis accounts for the vast majority of cancer deaths. The unique challenges for
treating metastases include their small size, high multiplicity and dispersion to diverse organ …

Biomedical metal–organic framework materials: perspectives and challenges

A Wang, M Walden, R Ettlinger… - Advanced Functional …, 2023 - Wiley Online Library
Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: a review of the state of the art

S Weber, A Zimmer, J Pardeike - European Journal of Pharmaceutics and …, 2014 - Elsevier
Drug delivery by inhalation is a noninvasive means of administration that has following
advantages for local treatment for airway diseases: reaching the epithelium directly …