Objective Skull base chordoma (SBC) is rare and one of the most challenging diseases to
treat. We aimed to assess the optimal timing of adjuvant radiation therapy (RT) and to …

Opinion Statement Management of chordoma along the cranial-spinal axis is a major
challenge for both skull base and spinal surgeons. Although chordoma remains a rare …

OBJECTIVE In the last 2 decades, the endoscopic endonasal approach in the treatment of
clival chordomas has evolved to be a viable strategy to achieve maximal safe resection of …

Background: The aim of the study was to describe our initial experience with the high-
definition three-dimensional (3D) exoscope for middle ear surgery versus the operating …

Background: Skull base chordoma is a rare tumor with low-grade malignancy and a high
recurrence rate, the factors affecting the prognosis of patients need to be further studied. For …

Background Skull base chordomas (SBCs) are rare malignant bone tumors with dismal long-
term local control. Endoscopic endonasal surgeries (EESs) are increasingly adopted to …

Simple Summary We report the experience of our institution in treating clival chordomas
over 20 years and systematically review the recent literature, highlighting factors associated …

Background Endoscopic transnasal transclival intradural surgery is limited by a high
postoperative cerebrospinal fluid leak rate. The aim of this study was to investigate the role …

Skull base tumors constitute one of the established indications for particle therapy,
specifically proton therapy. However, a number of prognostic factors, practical clinical …

Background The role of endonasal endoscopic surgery and radiotherapy in the treatment of
skull base chordomas remains unclear. Objective We investigated the effect of endonasal …