Abstract c-Jun N-terminal kinase (JNK) signalling regulates both cancer cell apoptosis and
survival. Emerging evidence show that JNK promoted tumour progression is involved in …

Pyridine derivatives are the most common and significant heterocyclic compounds, which
show their fundamental characteristics to various pharmaceutical agents and natural …

BACKGROUND Pyropia yezoensis, rich in porphyran, is a medicine‐edible red alga. In the
present study, the physicochemical characteristics, conformational states and antitumor …

The JNKs are members of mitogen-activated protein kinases (MAPK) which regulate many
physiological processes including inflammatory responses, macrophages, cell proliferation …

Aim: A fragment-based design and synthesis of three novel series of aminopyridone-linked
benzimidazoles as potential anticancer candidates with significant CDK9 inhibition was …

Squaraine dyes are a family of compounds known for their relevant photophysical and
photochemical properties potentially useful as photosensitizing agents. Since pyridines …

Cancer is a heterogeneous disease characterized by an abnormal and uncontrolled division
of the cells leading to tumors that invade the adjacent normal tissues. After cardiovascular …

Endometriosis has been shown to increase the risk of gynecological cancers. However, the
effect of gestrinone, a clinical endometriosis drug, on gynecological cancers remains …

A simple approach was applied for the regioselective synthesis of various pyridine‐2‐one
derivatives or annulated pyridine as novel heterocyclic systems from the reaction of …

Cancer is a disease of mutation and lifestyle modifications. A large number of normal genes
can transform normal cells to cancer cells due to their deregulations including …