Purpose Sepsis is recognized as a global public health problem, but the proportion due to
hospital-acquired infections remains unclear. We aimed to summarize the epidemiological …

Severe sepsis is a leading cause of death in the United States and the most common cause
of death among critically ill patients in non-coronary intensive care units (ICU). Respiratory …

Animals live in symbiosis with numerous microbe species. While some can protect hosts
from infection and benefit host health, components of the microbiota or changes to the …

Sepsis has been around since the dawn of time, having been described for more than 2000
years, although clinical definitions are recent. The consensus sepsis definitions have …

One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …

Objective: To determine recent trends in rates of hospitalization, mortality, and hospital case
fatality for severe sepsis in the United States. Design: Trend analysis for the period from …

The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm,
apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical …

Sepsis, a leading cause of morbidity and mortality throughout the world, is a clinical
syndrome with signs and symptoms relating to an infectious event and the consequent …

BACKGROUND: Bloodstream infections are a major cause of morbidity and mortality in
adults. Bloodstream infections should be reassessed periodically because of increased …

Sepsis is defined as life-threatening organ dysfunction caused by a host response to
infection and represents a spectrum of disease severity ranging from bacteremia to septic …