Melanin-targeting radiotracers and their preclinical, translational, and clinical status: from past to future
X Zhang, Z Lin, Y Feng, F Kang, J Wang… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Melanin is one of the representative biomarkers of malignant melanoma and a potential
target for diagnosis and therapy. With advancements in chemistry and radiolabeling …
target for diagnosis and therapy. With advancements in chemistry and radiolabeling …
Ultrasensitive detection of malignant melanoma using PET molecular imaging probes
A Pyo, DY Kim, H Kim, D Lim… - Proceedings of the …, 2020 - National Acad Sciences
Malignant melanoma has one of the highest mortality rates of any cancer because of its
aggressive nature and high metastatic potential. Clinical staging of the disease at the time of …
aggressive nature and high metastatic potential. Clinical staging of the disease at the time of …
Synthesis and evaluation of 18F-labeled procainamide as a PET imaging agent for malignant melanoma
A Pyo, M Yun, B Song, SY Kwon, JJ Min… - Bioorganic & Medicinal …, 2023 - Elsevier
Malignant melanoma has an aggressive nature and a high metastatic propensity resulting in
the highest mortality rate of any skin cancer. In this study, we synthesized 18 F-labeled …
the highest mortality rate of any skin cancer. In this study, we synthesized 18 F-labeled …
Synthesis and Preclinical Evaluation of a 68Ga-Labeled Pyridine-Based Benzamide Dimer for Malignant Melanoma Imaging
T Wang, P Xu, J Fang, C Li, X Zeng, J Liu… - Molecular …, 2022 - ACS Publications
Benzamide (BZA), a small molecule that can freely cross cell membranes and bind to
melanin, has served as an effective targeting group for melanoma theranostics. In this study …
melanin, has served as an effective targeting group for melanoma theranostics. In this study …
KSNM60: The History of Radiopharmaceutical Sciences in Korea
A number of researchers in Korea have tried to set-up the production of radionuclides and
develop new radiopharmaceuticals for several decades. Thanks to their 60-year endeavor to …
develop new radiopharmaceuticals for several decades. Thanks to their 60-year endeavor to …
[PDF][PDF] Discovery, characterization and optimization of bidentate protein ligands
M Catalano - 2020 - research-collection.ethz.ch
500 Da), which confer a benefit to patients thanks to their interaction with cognate protein
targets. The discovery of binding molecules and the quantitative characterization of their …
targets. The discovery of binding molecules and the quantitative characterization of their …