Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment

Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …

The role of lncRNA NEAT1 in human cancer chemoresistance

F Long, X Li, J Pan, H Ye, C Di, Y Huang, J Li… - Cancer Cell …, 2024 - Springer
Chemotherapy is currently one of the most effective methods in clinical cancer treatment.
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …

Harnessing the power of clustered regularly interspaced short palindromic repeats (CRISPR) based microfluidics for next-generation molecular diagnostics

R Kaur, S Gupta, A Chauhan, V Mishra… - Molecular Biology …, 2024 - Springer
CRISPR-based (Clustered regularly interspaced short palindromic repeats-based)
technologies have revolutionized molecular biology and diagnostics, offering …

Ru(II) Complexes with Absorption in the Photodynamic Therapy Window: 1O2 Sensitization, DNA Binding, and Plasmid DNA Photocleavage

SJ Steinke, MN Dunbar, MA Amalfi Suarez… - Inorganic …, 2024 - ACS Publications
Two Ru (II) complexes,[Ru (pydppn)(bim)(py)] 2+[2; pydppn= 3-(pyrid-2′-yl)-4, 5, 9, 16-
tetraaza-dibenzo [a, c] naphthacene; bim= 2, 2′-bisimidazole; py= pyridine] and [Ru …

Encapsulation of a small-molecule drug based on substituted 2-aminothiophenes in calcium carbonate carriers for therapy of melanoma

TE Karpov, A Rogova, DR Akhmetova… - Biomaterials …, 2024 - pubs.rsc.org
Although small molecule drugs are widely used in chemotherapy, their low bioavailability,
low-concentrated dose in the tumor zone, systemic toxicity, and chemoresistance can …

[HTML][HTML] A Natural Compound-Empowered Podophyllotoxin Prodrug Nanoassembly Magnifies Efficacy-Toxicity Benefits in Cancer Chemotherapy

Z Lin, Y Wang, W Li, F Sun, Q Lv, S Zhang, X Liu… - Asian Journal of …, 2024 - Elsevier
Small-molecule prodrug nanoassembly technology with a unique advantage in off-target
toxicity reduction has been widely used for antitumor drug delivery. However, prodrug …

Acidic Environment-Responsive Metal Organic Framework-Mediated Dihydroartemisinin Delivery for Triggering Production of Reactive Oxygen Species in Drug …

X Yan, X Zhao, M Fan, W Zheng, G Zhu… - International Journal of …, 2024 - Taylor & Francis
Background Dihydroartemisinin (DHA) has emerged as a promising candidate for
anticancer therapy. However, the application of DHA in clinics has been hampered by …

Engineering nanoparticles for cancer immunotherapy: Current achievements, key considerations and future perspectives

MU Farooq, CH Lawrie, NN Deng - Chemical Engineering Journal, 2024 - Elsevier
Cancer immunotherapies, which rely on training or stimulating our immune system, are
revolutionizing the way of cancer treatment. In recent years, these revolutionary weapons …

[HTML][HTML] Extraction Optimization and Anti-Tumor Activity of Polysaccharides from Chlamydomonas reinhardtii

Z Liang, L Xiong, Y Zang, Z Tang, Z Shang, J Zhang… - Marine Drugs, 2024 - mdpi.com
Chlamydomonas reinhardtii polysaccharides (CRPs) are bioactive compounds derived from
C. reinhardtii, yet their potential in cancer therapy remains largely unexplored. This study …

[HTML][HTML] A comprehensive review and advanced biomolecule-based therapies for osteoporosis

M Ali, YS Kim - Journal of Advanced Research, 2024 - Elsevier
Background The prevalence of osteoporosis (OP) on a global scale is significantly elevated
that causes life threatening issues. The potential of groundbreaking biomolecular …