Streptococcus pyogenes is a major human pathogen responsible for numerous diseases
ranging from uncomplicated skin and throat infections to severe, life threatening invasive …

Pulsed-spray thrombolysis is accomplished through forceful injection of a spray of highly
concentrated urokinase into clot by using catheters with multiple side holes. We previously …

Various plasminogen activators have been routinely used for the treatment of thrombotic
diseases. However, these agents possess various problems eg short half life and other …

Recombinant tissue plasminogen activator restores perfusion... : Critical Care Medicine
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura …

Atherosclerosis is probably caused by multiple interacting factors such as disturbed lipid
metabolism; endothelial cell damage, leading to platelet aggregation and monocyte …

Increases in plasma creating kinase-MB (MB CK) were correlated with the onset of coronary
artery reperfusion determined angiographically in 32 patients with acute myocardial …

The development of a fibrinolytic system with long circulation time, high thrombus targeting,
efficient thrombus penetration, effective thrombolysis, and minimal hemorrhagic risk remains …

The role of Asn-linked oligosaccharide in the functional properties of both human tissue-type
plasminogen activator (t-PA) and a genetic variant of t-PA was studied. Nonglycosylated and …

Fulminant meningococcemia defines a life-threatening disease with acute onset, severe
septic shock, and progressive hemorrhagic necrosis of the skin. Despite advances in …

BACKGROUND Chimeric molecules comprising the A-chain of tissue-type plasminogen
activator (t-PA) and the catalytic domain of urokinase-type plasminogen activator (u-PA) …