Non-cytotoxic protein conjugates
K Foster, J Chaddock, C Penn, KR Aoki… - US Patent …, 2012 - Google Patents
PULGYDLMFSFVBL-SMFNREODSA-N nociceptin Chemical compound C ([C@@ H](C (=
O) N [C@ H](C (= O) NCC (= O) N [C@@ H](C) C (= O) N [C@@ H](CCCNC (N)= N) C (= O) …
O) N [C@ H](C (= O) NCC (= O) N [C@@ H](C) C (= O) N [C@@ H](CCCNC (N)= N) C (= O) …
Fusion proteins
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2011 - Google Patents
A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a
fragment thereof, which protease or protease fragment is capable of cleaving a protein of the …
fragment thereof, which protease or protease fragment is capable of cleaving a protein of the …
Fusion proteins
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2016 - Google Patents
7,244,436 B2 7/2007 Donovan 7,244,437 B2 7/2007 Donovan 7,262.291 B2 8, 2007
Donovan 7,276.473 B2 10/2007 Sachs 7,413,742 B2 8, 2008 Donovan 7,419,676 B2 …
Donovan 7,276.473 B2 10/2007 Sachs 7,413,742 B2 8, 2008 Donovan 7,419,676 B2 …
Non-cytotoxic protein conjugates
K Foster, J Chaddock, C Penn, KR Aoki… - US Patent …, 2013 - Google Patents
SLZIZIJTGAYEKK-CIJSCKBQSA-N molport-023-220-247 Chemical compound C ([C@@
H](C (= O) N [C@@ H](C) C (= O) N [C@@ H]([C@@ H](C) CC) C (= O) N [C@@ H](CC (O) …
H](C (= O) N [C@@ H](C) C (= O) N [C@@ H]([C@@ H](C) CC) C (= O) N [C@@ H](CC (O) …
Non-cytotoxic protein conjugates
K Foster, J Chaddock, C Penn, K Aoki, J Francis… - US Patent …, 2013 - Google Patents
The present invention is directed to non-cytotoxic protein conjugates for inhibition or
reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates …
reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates …
Fusion proteins
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2013 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
Fusion proteins
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2013 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
Treatment of pain
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2015 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
Non-cytotoxic protein conjugates
K Foster, J Chaddock, C Penn, KR Aoki… - US Patent …, 2014 - Google Patents
The present invention is directed to non-cytotoxic protein conjugates for inhibition or
reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates …
reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates …
Fusion proteins
K Foster, J Chaddock, P Marks, P Stancombe… - US Patent …, 2015 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …