Cell lines are still a tool of choice for many fields of biomedical research, including oncology.
Although cancer is a very complex disease, many discoveries have been made using …

The process of evaluating the efficacy and toxicity of drugs is important in the production of
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …

Renal cell carcinoma (RCC) refers to renal-epithelial cancer, which represents over 90% of
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …

Background Relapse and metastasis in colorectal cancer (CRC) are often attributed to
cancer stem-like cells (CSCs), as small sub-population of tumor cells with ability of drug …

Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …

With excellent physicochemical properties, inorganic nanomaterials (INMs) have exhibited a
series of attractive applications in biomedical fields. Biological barriers prevent successful …

Three-dimensional cell culture has revolutionized cellular biology research and opened the
door to novel discoveries in terms of cellular behavior and response to microenvironment …

A series of stable and ready-to-use bioinks have been developed based on the xeno-free
and tunable hydrogel (VitroGel) system. Cell laden scaffold fabrication with optimized …

Cancer stem cells have been shown to be important in tumorigenesis processes, such as
tumor growth, metastasis, and recurrence. As such, many three-dimensional models have …

Therapy resistance represents a clinical challenge for advanced non-small cell lung cancer
(NSCLC), which still remains an incurable disease. There is growing evidence that cancer …