Abstract Mucin 1 (MUC1) is a membrane‑bound, highly glycosylated protein that is
overexpressed in all stages of malignant transformation. Overexpression of MUC1 together …

Mucin-type GalNAc O-glycosylation is one of the most abundant and unique post-
translational modifications. The combination of proteome-wide mapping of GalNAc O …

Introduction The cellular behavior in normal mammary gland development and the
progression of breast cancer is like the relationship between an object and its mirror image …

Aberrant expression of O-glycans is a hallmark of epithelial cancers. Mucin-type O-
glycosylation is initiated by a large family of UDP-GalNAc: polypeptide N …

Background Re-capture of the differences between tumor and normal tissues observed at
the patient level in cell cultures and animal models is critical for applications of these cancer …

The mitochondrial pro-apoptotic protein SMAC/Diablo participates in apoptosis by
negatively regulating IAPs and activating caspases, thus encouraging apoptosis …

Abstract Polypeptide N-acetylgalactosaminyl transferase-6 (GALNT6), a member of the N-
acetyl-D-galactosamine transferase family, was shown to be over-expression in mammary …

Background Obesity is a major risk factor for dysglycemic disorders, including type 2
diabetes (T2D). However, there is wide phenotypic variation in metabolic profiles. Tissue …

Protein glycosylation perturbations are implicated in a variety of diseases, including cancer.
Aberrant glycosylation in cancer is frequently attributed to altered expression of polypeptide …

Abstract Polypeptide N‑acetylgalactosaminyltransferase 6 (GALNT6), which is involved in
the initiation of O‑glycosylation, has been reported to play crucial roles in mammary …