[HTML][HTML] Retinoid X receptors: X-ploring their (patho) physiological functions
Retinoid X receptor (RXR) belongs to a family of ligand-activated transcription factors that
regulate many aspects of metazoan life. A class of nuclear receptors requires RXR as …
regulate many aspects of metazoan life. A class of nuclear receptors requires RXR as …
Improving metabolic control leads to better working memory in adults with type 2 diabetes
CM Ryan, MI Freed, JA Rood, AR Cobitz… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—The goals of this study were to determine whether improvements in metabolic
control can ameliorate the cognitive dysfunction associated with type 2 diabetes and …
control can ameliorate the cognitive dysfunction associated with type 2 diabetes and …
Activation of peroxisome proliferator–activated receptor (PPAR) δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty …
U Risérus, D Sprecher, T Johnson, E Olson… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Pharmacological use of peroxisome proliferator–activated receptor (PPAR) δ
agonists and transgenic overexpression of PPARδ in mice suggest amelioration of features …
agonists and transgenic overexpression of PPARδ in mice suggest amelioration of features …
Improved insulin resistance and lipid metabolism by cinnamon extract through activation of peroxisome proliferator‐activated receptors
X Sheng, Y Zhang, Z Gong, C Huang… - PPAR research, 2008 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs) are transcriptional factors involved in
the regulation of insulin resistance and adipogenesis. Cinnamon, a widely used spice in …
the regulation of insulin resistance and adipogenesis. Cinnamon, a widely used spice in …
Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
M Bajaj, S Suraamornkul, P Piper… - The journal of …, 2004 - academic.oup.com
The effect of pioglitazone (PIO) on plasma adiponectin concentration, endogenous glucose
production (EGP), and hepatic fat content (HFC) was studied in 11 type 2 diabetic patients …
production (EGP), and hepatic fat content (HFC) was studied in 11 type 2 diabetic patients …
Adipose tissue in health and disease
I Harvey, A Boudreau, JM Stephens - Open biology, 2020 - royalsocietypublishing.org
Adipose, or fat, tissue (AT) was once considered an inert tissue that primarily existed to store
lipids, and was not historically recognized as an important organ in the regulation and …
lipids, and was not historically recognized as an important organ in the regulation and …
Whole body fat: content and distribution
Obesity and its co-morbidities, including type II diabetes, insulin resistance and
cardiovascular diseases, have become one of the biggest health issues of present times …
cardiovascular diseases, have become one of the biggest health issues of present times …
[HTML][HTML] Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents
KF Petersen, S Dufour, GI Shulman - PLoS medicine, 2005 - journals.plos.org
Background Insulin resistance is the best predictor for the development of type 2 diabetes.
Recent studies have shown that young, lean, insulin-resistant (IR) offspring of parents with …
Recent studies have shown that young, lean, insulin-resistant (IR) offspring of parents with …
Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence
M Diamant, RJ Heine - Drugs, 2003 - Springer
Type 2 diabetes mellitus is characterised by insulin resistance as well as progressive
pancreatic β cell dysfunction. The cornerstone of current oral blood-glucose lowering …
pancreatic β cell dysfunction. The cornerstone of current oral blood-glucose lowering …
Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals
R Rabøl, KF Petersen, S Dufour… - Proceedings of the …, 2011 - National Acad Sciences
Skeletal muscle insulin resistance has been implicated in the pathogenesis of nonalcoholic
fatty liver disease (NAFLD) and atherogenic dyslipidemia associated with the metabolic …
fatty liver disease (NAFLD) and atherogenic dyslipidemia associated with the metabolic …