The effects of calcitonin gene-related peptide (CGRP) on atherosclerosis remain unclear.
We used apolipoprotein E-deficient (ApoE−/−) mice to generate double-knockout ApoE …

Objectives Dietary capsaicin from spicy foods has potential benefits for those with
cardiometabolic diseases (CMDs). However, to our knowledge there is no evidence linking …

Pain signals are relayed to the brain via a nociceptive system, and in rare cases, this
nociceptive system contains genetic variants that can limit the pain response. Here, we …

Photobiomodulation (PBM) is emerging as a promising non-invasive approach for managing
inflammatory skin conditions. However, its precise molecular mechanisms, especially within …

Pharmacological doses of zinc oxide (ZnO) have been widely used in pig industry to control
post-weaning diarrhea (PWD) symptoms exacerbated by enterotoxigenic Escherichia coli F4 …

Take Home Message: Capsaicin modified inflammatory response and caused toxicity in
bronchial epithelial cultures from patients with COPD. More importantly, capsaicin …

An increasing number of studies have shown that nicotinamide mononucleotide (NMN) can
inhibit not only ageing but also oxidative stress and inflammatory reactions by improving …

BACKGROUND Hydrogen sulfide (H 2 S) is a recently discovered gaseous neurotransmitter
in the nervous and gastrointestinal systems. It exerts its effects through multiple signaling …

Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel that
interacts with several intracellular proteins in vivo, including calmodulin and …

dihydroxy‐8Z, 11Z, 14Z, 17Z‐eicosatetraenoic acid (5, 6‐DiHETE) is an eicosapentaenoic
acid‐derived lipid metabolite, which we previously detected in inflamed mouse colon. In this …