Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults. Vascular
pericyte degeneration is the predominant clinical manifestation of DR, yet the mechanism …

Long noncoding RNAs (lncRNAs) have important roles in diverse biological processes. Our
previous study has revealed that lncRNA-MALAT1 deregulation is implicated in the …

The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells
covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully …

Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …

We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

The retina was first described by Herophilus of Chalcedon around 300 bc. It was named by
Rufos of Ephesus (c. 110 ad) and appeared to early anatomists as a surrounding net which …

Pericytes are specialized mural cells located at the abluminal surface of capillary blood
vessels, embedded within the basement membrane. In the vascular network these …