Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

Importance Cannabis use and potency of cannabis have increased during the past 2
decades. If the association between cannabis use and schizophrenia is causal, this should …

Childhood maltreatment represents a form of trauma capable of altering fundamental
neurobiological properties and negatively impacting neurodevelopmental processes. An …

The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …

Brain Derived Neurotrophic Factor (BDNF) has been linked to cognitive symptoms of
schizophrenia, which has been documented in previous reviews by several authors …

Imaging and postmortem studies have revealed disturbed oligodendroglia-related
processes in patients with schizophrenia and provided much evidence for disturbed …

Schizophrenia is a debilitating psychiatric illness that remains poorly understood. While the
bulk of symptomatology has classically been associated with disrupted brain functioning …

Schizophrenia is regarded as a neurodevelopmental disorder with its course progressing
throughout life. However, the aetiology and development of schizophrenia are still under …