Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

Stem cells are undifferentiated cells that are present in the embryonic, fetal, and adult stages
of life and give rise to differentiated cells that make up the building blocks of tissue and …

Haploids and double haploids are important resources for studying recessive traits and have
large impacts on crop breeding, but natural haploids are rare in animals. Mammalian …

The ability to reprogram adult cells into stem cells has raised hopes for novel therapies for
many human diseases. Typical stem cell reprogramming protocols involve expression of a …

Physical and mental health and hormonal imbalance are associated with the problems
related to infertility and reproductive disorders. The rate of infertility has increased globally …

Orthotropic liver transplantation is the only established treatment for end-stage liver
diseases. Utilization of hepatocyte transplantation and bio-artificial liver devices as …

Although somatic cells can be successfully programmed to create pluripotent stem cells by
ectopically expressing defined transcriptional factors, reprogramming efficiency is low and …

Atropine has been used for more than a century to arrest myopia progression. Compelling
evidence of its protective effect has been reported in well-designed clinical studies, mainly …

The successful derivation of human induced pluripotent stem cells (hiPSCs) by
dedifferentiation of somatic cells offers significant potential to overcome obstacles in the field …

This 'Have you seen?'features important insights into genomic aberrations of pluripotent
stem cells from studies recently published in Nature, Cell Stem Cell and Cell Death & …