Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy
M Chehelgerdi, M Chehelgerdi… - Molecular cancer, 2024 - Springer
The CRISPR system is a revolutionary genome editing tool that has the potential to
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …
Metabolic heterogeneity, plasticity, and adaptation to “glutamine addiction” in cancer cells: the role of glutaminase and the GTωA [glutamine transaminase—ω …
AJL Cooper, T Dorai, JT Pinto, TT Denton - Biology, 2023 - mdpi.com
Simple Summary Many types of cancer cells utilize the common amino acid l-glutamine to
maintain their metabolic demands for energy and the nitrogen required for DNA synthesis …
maintain their metabolic demands for energy and the nitrogen required for DNA synthesis …
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
T Uo, KK Ojo, CCT Sprenger, KS Epilepsia… - Molecular Cancer …, 2024 - AACR
Metastatic castration-resistant prostate cancer remains incurable regardless of recent
therapeutic advances. Prostate cancer tumors display highly glycolytic phenotypes as the …
therapeutic advances. Prostate cancer tumors display highly glycolytic phenotypes as the …
A new tumorgraft panel to accelerate precision medicine in prostate cancer
C Béraud, N Bidan, M Lassalle, H Lang… - Frontiers in …, 2023 - frontiersin.org
Background Despite the significant advances in the management of advanced prostate
cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in …
cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in …
[HTML][HTML] Experimental models of tumor growth in soft tissue sarcomas
MS Tretyakova, UA Bokova… - Вестник Российского …, 2023 - cyberleninka.ru
Soft tissue sarcomas are rare tumors (about 1% of all malignant neoplasms) and include
more than 70 histological subtypes, the pathogenetic features of which remain unclear. This …
more than 70 histological subtypes, the pathogenetic features of which remain unclear. This …
[HTML][HTML] Метаболический профиль у пациентов с раком предстательной железы
ЕВ Помешкин, АВ Смирнов, СВ Попов… - Research'n Practical …, 2023 - cyberleninka.ru
Цель исследования. Оценить уровни метаболических маркеров у больных раком
предстательной железы (РПЖ) в сравнении с пациентами, имеющими …
предстательной железы (РПЖ) в сравнении с пациентами, имеющими …