The existence of polycyclic aromatic hydrocarbons (PAHs) in ambient air is an escalating
concern worldwide because of their ability to cause cancer and induce permanent changes …

Epigenetic changes constitute one of the processes that is involved in the mechanisms of
carcinogenicity. They include dysregulation of DNA methylation processes, disruption of …

Abstract Benzo (a) pyrene (BaP), the earliest and most significant carcinogen among
polycyclic aromatic hydrocarbons (PAHs), has been found in foods, tobacco smoke, and …

Abstract Benzo [a] pyrene (BaP) exposure has been associated with an increased risk of
carcinogenesis. We investigated the effects of BaP on cell viability, the promoter methylation …

Abstract Benzo [a] pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), is implicated in
many developmental and behavioral adverse outcomes in offspring of exposed parents. The …

The Transformics Assay is an in vitro test which combines the BALB/c 3T3 Cell
Transformation Assay (CTA) with microarray transcriptomics. It has been shown to improve …

Epigenetic mutations caused by pollutants are possibly linked to many diseases. Benzo (a)
pyrene (BaP) is one of the most representative air pollutants and has aroused wide concern …

表观遗传学是一门重要的生命学科, 主要包括DNA 的甲基化, 组蛋白修饰以及非编码RNA
等内容, 其中任何一方面的表观遗传学变化对生物体的生命过程都有重要的影响 …

近年研究发现, 环境致癌物苯并(a) 芘的致癌机制除遗传毒性外, 可引起全基因组甲基化减低,
抑癌基因甲基化升高及原癌基因甲基化降低, 亦可引起微RNA 表达升高或降低, 长链非编码RNA …

A policiklusos aromás szénhidrogének olyan kondenzált aromás gyűrűkből álló
szerkezetek, amelyek a környezetünk minden szférájában jelen vannak (GHOSAL et al …