The circadian timing system (CTS) controls various biological functions in mammals
including xenobiotic metabolism and detoxification, immune functions, cell cycle events …

The roles of the epidermal growth factor receptor (EGFR) signaling pathway in various
cancers including breast, bladder, brain, colorectal, esophageal, gastric, head and neck …

The mechanisms by which angiotensin II (AngII) elevates blood pressure and enhances end-
organ damage seem to be distinct. However, the signal transduction cascade by which AngII …

Overexpression and mutational activation of the epidermal growth factor receptor (EGFR)
plays an important role in the pathogenesis of non–small cell lung cancer (NSCLC). EGFR …

Liver fibrosis is a wound-healing response caused by the abnormal accumulation of
extracellular matrix, which is produced by activated hepatic stellate cells (HSCs). Most …

Mutational activation of the epidermal growth factor receptor (EGFR) is a major player in the
pathogenesis of non-small cell lung cancer (NSCLC). NSCLC patients with constitutively …

AIM To screen five potential pharmacological substances specifically targeting EGF-R,
MAPK, mTOR, or PI3K for their antiproliferative effects, possible impact on cell viability, as …

An adverse reaction of dry skin occurs frequently during treatment with anticancer epidermal
growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). In this study, we conducted …

Breve evolución histórica del cáncer Page 32 Breve evolución histórica del cáncer Brief
historical evolution of cancer Se revisa la historia del cáncer desde tiempos remotos en la …

Receptor tyrosine kinases, mediators of a variety of critical cellular functions, contribute to
tumor progression and metastasis. The epidermal growth factor receptor (EGFR), a member …