Diabetes mellitus (DM) is a severe chronic metabolic disease with increased mortality and
morbidity. The pathological progression of DM is intimately connected with the formation and …

The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …

Caffeine, a xanthine alkaloid compound, is consumed widely and daily by humans, as it is
present in several regular beverages such as tea, coffee, soda beverages, and some drugs …

Lycopene, a natural pigment that mainly exists in the mature fruit of tomatoes, has gained
increasing attention due to its protective effects against obesity and diabetes. The aim of this …

The relatively rapid shift from consuming preagricultural wild foods for thousands of years, to
consuming postindustrial semi-processed and ultra-processed foods endemic of the …

Background Brazil has over 40,000 varied plant species rich in phytochemicals, expressing
20% of the world's flora. Due to its immense diversity, Brazil presents a high potential to …

Coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a newly
discovered highly pathogenic virus that was declared pandemic in March 2020 by the World …

Diabetes is a systemic disease that can cause brain damage such as synaptic impairments
in the hippocampus, which is partly because of neuroinflammation induced by …

Diabetes mellitus is associated with an increased risk of Alzheimer's dementia and cognitive
decline. The cause of neurodegeneration in chronic diabetic patients remains unclear …

Aging is the main risk factor for Alzheimer's disease (AD); being associated with
conspicuous changes on microglia activation. Aged microglia exhibit an increased …