[HTML][HTML] Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and …

Y Lu, Q Luo, X Jia, JP Tam, H Yang, Y Shen… - Journal of Pharmaceutical …, 2023 - Elsevier
Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Multi‐responsive biodegradable cationic nanogels for highly efficient treatment of tumors

X Li, H Sun, H Li, C Hu, Y Luo, X Shi… - Advanced Functional …, 2021 - Wiley Online Library
The facile preparation, modular design, and multi‐responsiveness are extremely critical for
developing pervasive nanoplatforms to meet heterogeneous applications. Here, cationic …

GSH/APE1 cascade-activated nanoplatform for imaging therapy resistance dynamics and enzyme-mediated adaptive ferroptosis

R Yue, M Zhou, X Li, L Xu, C Lu, Z Dong, L Lei, H Liu… - ACS …, 2023 - ACS Publications
Ferroptosis, as a type of programmed cell death process, enables effective damage to
various cancer cells. However, we discovered that persistent oxidative stress during …

[HTML][HTML] Charge-reversible and biodegradable chitosan-based microgels for lysozyme-triggered release of vancomycin

X Li, L Hetjens, N Wolter, H Li, X Shi, A Pich - Journal of advanced research, 2023 - Elsevier
Introduction High-dose drug administration for the conventional treatment of inflammatory
bowel disease induces cumulative toxicity and serious side effects. Currently, few reports …

Ultrasmall superparamagnetic iron oxide nanoparticles: A next generation contrast agent for magnetic resonance imaging

C Chen, J Ge, Y Gao, L Chen, J Cui… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
As a research hotspot, the development of magnetic resonance imaging (MRI) contrast
agents has attracted great attention over the past decades for improving the accuracy of …

[HTML][HTML] Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging

Z Zhao, M Li, J Zeng, L Huo, K Liu, R Wei, K Ni, J Gao - Bioactive Materials, 2022 - Elsevier
Iron oxide nanoparticle (IONP) with unique magnetic property and high biocompatibility
have been widely used as magnetic resonance imaging (MRI) contrast agent (CA) for long …

Ultrasound-enhanced precision tumor theranostics using cell membrane-coated and pH-responsive nanoclusters assembled from ultrasmall iron oxide nanoparticles

L Jia, X Li, H Liu, J Xia, X Shi, M Shen - Nano Today, 2021 - Elsevier
Abstract Design of novel theranostic nanoplatforms integrating precision dynamic imaging
modalities, tumor targeting ligands and therapeutic components with enhanced tumor …

Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1‐Weighted Magnetic Resonance Imaging and Imaging‐Guided Therapy of Tumors

J Yang, J Feng, S Yang, Y Xu, Z Shen - Small, 2023 - Wiley Online Library
Magnetic iron oxide nanoparticles (MIONs) based T2‐weighted magnetic resonance
imaging (MRI) contrast agents (CAs) are liver‐specific with good biocompatibility, but have …

Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma

Y Lu, Y Gao, H Yang, Y Hu, X Li - Military Medical Research, 2022 - Springer
Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical
resection, transplantation, radiofrequency ablation, and chemotherapy are unsatisfactory …