Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) in Disease Diagnosis: An Overview.
BS Kumar - Analytical Methods, 2023 - pubs.rsc.org
Tissue analysis, which is essential to histology and is considered the benchmark for the
diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery …
diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery …
Metabolomic profiling identified serum metabolite biomarkers and related metabolic pathways of colorectal cancer
C Zhang, S Zhou, H Chang, F Zhuang, Y Shi… - Disease …, 2021 - Wiley Online Library
Background. The screening and early detection of colorectal cancer (CRC) still remain a
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is …
Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
S Yan, S Wang, X Wang, W Dai, J Chu, M Cheng… - Frontiers in …, 2022 - frontiersin.org
Metabolic reprogramming plays a critical role in colorectal cancer (CRC). It contributes to
CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells …
CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells …
Tadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer
Y Shen, P Zhao, K Dong, J Wang, H Li, M Li, R Li… - Cancer & …, 2022 - Springer
Background Protein arginine methyltransferase 5 (PRMT5) is upregulated in multiple tumors
and plays a pivotal role in cancer cell proliferation. However, the role of PRMT5 in colorectal …
and plays a pivotal role in cancer cell proliferation. However, the role of PRMT5 in colorectal …
The effectiveness of glutathione redox status as a possible tumor marker in colorectal cancer
D Acevedo-León, L Monzó-Beltrán… - International journal of …, 2021 - mdpi.com
The role of oxidative stress (OS) in cancer is a matter of great interest due to the implication
of reactive oxygen species (ROS) and their oxidation products in the initiation of …
of reactive oxygen species (ROS) and their oxidation products in the initiation of …
Identification of novel core genes involved in Malignant transformation of inflamed colon tissue using a computational biology approach and verification in murine …
AV Markov, IA Savin, MA Zenkova… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a complex and multifactorial systemic disorder of the
gastrointestinal tract and is strongly associated with the development of colorectal cancer …
gastrointestinal tract and is strongly associated with the development of colorectal cancer …
Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas—A Preliminary Study
K Skubisz, K Dąbkowski, E Samborowska… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a significant problem worldwide. Most cancers are
diagnosed at an advanced stage. Limited knowledge of the pathogenesis of pancreatic …
diagnosed at an advanced stage. Limited knowledge of the pathogenesis of pancreatic …
Metabolically active zones involving fatty acid elongation delineated by DESI-MSI correlate with pathological and prognostic features of colorectal cancer
Colorectal cancer (CRC) is the second leading cause of cancer deaths. Despite recent
advances, five-year survival rates remain largely unchanged. Desorption electrospray …
advances, five-year survival rates remain largely unchanged. Desorption electrospray …
KAT2A affects tumor metabolic reprogramming in colon cancer progression through epigenetic activation of E2F1
X Han, J Chen - Human Cell, 2022 - Springer
Abstract Lysine acetyltransferase 2 A (KAT2A) has been implicated in tumorigenesis;
nevertheless, the mechanism underlying its tumor-initiating effect remains elusive. In the …
nevertheless, the mechanism underlying its tumor-initiating effect remains elusive. In the …
LC–MS-based serum metabolomics analysis for the screening and monitoring of colorectal cancer
Y Yi, J Wang, C Liang, C Ren, X Lian, C Han… - Frontiers in …, 2023 - frontiersin.org
Background Colorectal Cancer (CRC) is a prevalent digestive system tumour with significant
mortality and recurrence rates. Serum metabolomics, with its high sensitivity and high …
mortality and recurrence rates. Serum metabolomics, with its high sensitivity and high …