Genetics of obesity in humans: a clinical review
R Mahmoud, V Kimonis, MG Butler - International journal of molecular …, 2022 - mdpi.com
Obesity is a complex multifactorial disorder with genetic and environmental factors. There is
an increase in the worldwide prevalence of obesity in both developed and developing …
an increase in the worldwide prevalence of obesity in both developed and developing …
[HTML][HTML] Prader-willi syndrome
SB Cassidy, S Schwartz, JL Miller, DJ Driscoll - Genetics in medicine, 2012 - Elsevier
Prader-Willi syndrome is characterized by severe infantile hypotonia with poor suck and
failure to thrive; hypogonadism causing genital hypoplasia and pubertal insufficiency; …
failure to thrive; hypogonadism causing genital hypoplasia and pubertal insufficiency; …
Growth Hormone Research Society workshop summary: consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome
CL Deal, M Tony, C Höybye, DB Allen… - The Journal of …, 2013 - academic.oup.com
Context: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been
used by the medical community and advocated by parental support groups since its …
used by the medical community and advocated by parental support groups since its …
Long-term growth hormone therapy changes the natural history of body composition and motor function in children with Prader-Willi syndrome
AL Carrel, SE Myers, BY Whitman… - The Journal of …, 2010 - academic.oup.com
Abstract Background: Children with Prader-Willi syndrome (PWS) have decreased muscle
mass, hypotonia, and impaired linear growth. Recombinant human GH (hGH) treatment …
mass, hypotonia, and impaired linear growth. Recombinant human GH (hGH) treatment …
[HTML][HTML] Review of Prader-Willi syndrome: the endocrine approach
Prader-Willi syndrome (PWS) is a complex genetic disorder with implications on the
endocrine and neurologic systems, metabolism, and behavior. Early in life, PWS is …
endocrine and neurologic systems, metabolism, and behavior. Early in life, PWS is …
Eight years of growth hormone treatment in children with Prader-Willi syndrome: maintaining the positive effects
NE Bakker, RJ Kuppens… - The Journal of …, 2013 - academic.oup.com
Background: The most important reason for treating children with Prader-Willi syndrome
(PWS) with GH is to optimize their body composition. Objectives: The aim of this ongoing …
(PWS) with GH is to optimize their body composition. Objectives: The aim of this ongoing …
Prader-Willi syndrome: An uptodate on endocrine and metabolic complications
G Muscogiuri, G Formoso, G Pugliese… - Reviews in Endocrine …, 2019 - Springer
Prader-Willi syndrome (PWS) is a genetic disorder characterized by short stature, low lean
body mass, muscular hypotonia, mental retardation, behavioral abnormalities, dysmorphic …
body mass, muscular hypotonia, mental retardation, behavioral abnormalities, dysmorphic …
Endocrine manifestations and management of Prader-Willi syndrome
JE Emerick, KS Vogt - International journal of pediatric endocrinology, 2013 - Springer
Prader-Willi syndrome (PWS) is a complex genetic disorder, caused by lack of expression of
genes on the paternally inherited chromosome 15q11. 2-q13. In infancy it is characterized …
genes on the paternally inherited chromosome 15q11. 2-q13. In infancy it is characterized …
Prader Willi syndrome: genetics, metabolomics, hormonal function, and new approaches to therapy
KA Irizarry, M Miller, M Freemark… - Advances in …, 2016 - advancesinpediatrics.com
GENETICS OF PRADER WILLI SYNDROME Chromosomal localization PWS is the most
common syndromic obesity disorder, with a prevalence of 1 in 10,000 to 1 in 15,000 live …
common syndromic obesity disorder, with a prevalence of 1 in 10,000 to 1 in 15,000 live …
Contributing factors of mortality in Prader–Willi syndrome
J Proffitt, K Osann, B McManus… - American journal of …, 2019 - Wiley Online Library
Prader–Willi syndrome (PWS) is a multi‐system disorder resulting from a lack of paternal
gene expression in the 15q11. 2‐q13 region. Using databases compiled through response …
gene expression in the 15q11. 2‐q13 region. Using databases compiled through response …