IL-1 mediated auto-inflammatory diseases are characterised by episodes of unexplained
fever, generalized and localized inflammation. The characteristic symptoms predominantly …

Autoinflammatory disorders are commonly characterized by seemingly unprovoked systemic
inflammation mainly driven by cells and cytokines of the innate immune system. In many …

Overlapping clinical and pathomechanistic features can complicate the diagnosis and
treatment of inflammatory skin diseases, including psoriasis and atopic dermatitis (AD) …

Pathologic type I interferon (T1IFN) expression is a key feature in systemic lupus
erythematosus (SLE) that associates with disease activity. When compared to adult-onset …

Psoriasis is a chronic, inflammatory disease affecting the skin and joints. The pathogenesis
of this disease is associated with genetic, environmental and immunological factors …

A significant number of postural orthostatic tachycardia syndrome (POTS) patients have
platelet delta granule storage pool deficiency (δ-SPD). The etiology of POTS is unknown but …

Innate lymphoid cells (ILC) are members of a heterogeneous family with a lymphoid origin
that mimics the T helper (Th) cytokine profile. ILC are involved in early effector cytokine …

High-dose conditioning chemotherapy followed by autologous hematopoietic stem cell
transplantation (auto-HSCT) in systemic sclerosis (SSc), lupus erythematosus (SLE) …

The identification of novel, easily measurable biomarkers of inflammation might enhance the
diagnosis and management of immunological diseases (IDs). We conducted a systematic …

Der systemische Lupus erythematodes (SLE) ist eine systemische inflammatorische
Erkrankung, die jedes Organ des menschlichen Körpers betreffen und signifikanten …