ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs–threshold doses for tissue reactions in a …

FA Stewart, AV Akleyev, M Hauer-Jensen, JH Hendry… - Annals of the ICRP, 2012 - Elsevier
This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Radiation dose–volume effects in the lung

LB Marks, SM Bentzen, JO Deasy, JD Bradley… - International Journal of …, 2010 - Elsevier
The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The
rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no …

Association of radiation therapy with risk of adverse events in patients receiving immunotherapy: a pooled analysis of trials in the US food and drug administration …

MS Anscher, S Arora, C Weinstock, A Amatya… - JAMA …, 2022 - jamanetwork.com
Importance Immune checkpoint inhibitors (ICIs) and radiation therapy (RT) are widely used
to treat various cancers, but little data are available to guide clinicians on ICI use …

Effects of radiation on normal tissue: consequences and mechanisms

HB Stone, CN Coleman, MS Anscher… - The lancet …, 2003 - thelancet.com
Acute radiation damage is most prominent in tissues with rapidly proliferating cells, such as
in epithelial surfaces of the skin or alimentary tract. Symptoms develop when functional cells …

Animal models for medical countermeasures to radiation exposure

JP Williams, SL Brown, GE Georges… - Radiation …, 2010 - meridian.allenpress.com
Abstract Since September 11, 2001, there has been the recognition of a plausible threat
from acts of terrorism, including radiological or nuclear attacks. A network of Centers for …

Prediction of radiation pneumonitis by dose–volume histogram parameters in lung cancer—a systematic review

G Rodrigues, M Lock, D D'Souza, E Yu… - Radiotherapy and …, 2004 - Elsevier
BACKGROUND AND PURPOSE: To perform a systematic review of the predictive ability of
various dose–volume histogram (DVH) parameters (Vdose, mean lung dose (MLD), and …

Radiation pneumonitis and pulmonary fibrosis in non–small-cell lung cancer: Pulmonary function, prediction, and prevention

V Mehta - International journal of radiation oncology* biology …, 2005 - Elsevier
Although radiotherapy improves locoregional control and survival in patients with non-small-
cell lung cancer, radiation pneumonitis is a common treatment-related toxicity. Many …

Molecular mechanisms and treatment of radiation-induced lung fibrosis

NH Ding, J Jian Li, LQ Sun - Current drug targets, 2013 - ingentaconnect.com
Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer
patients that presents as a progressive pulmonary injury combined with chronic …

Radiation pulmonary toxicity: from mechanisms to management

PR Graves, F Siddiqui, MS Anscher… - Seminars in radiation …, 2010 - Elsevier
The goal of radiation therapy is to reduce or eliminate tumor burden while sparing normal
tissues from long-term injury. Thoracic radiation presents a unique challenge because of the …

Predictive value of dose-volume histogram parameters for predicting radiation pneumonitis after concurrent chemoradiation for lung cancer

K Tsujino, S Hirota, M Endo, K Obayashi… - International Journal of …, 2003 - Elsevier
Purpose: To clarify whether the percentage of pulmonary volume irradiated to> 20 Gy (V20)
is related to the incidence and grade of radiation pneumonitis (RP) in cases of lung cancer …