Recent advancements in nanomedicine for 'cold'tumor immunotherapy
Q Chen, T Sun, C Jiang - Nano-micro letters, 2021 - Springer
Although current anticancer immunotherapies using immune checkpoint inhibitors (ICIs)
have been reported with a high clinical success rate, numerous patients still bear …
have been reported with a high clinical success rate, numerous patients still bear …
Nanotechnology approaches in the current therapy of skin cancer
LN Borgheti-Cardoso, JSR Viegas… - Advanced Drug Delivery …, 2020 - Elsevier
Skin cancer is a high burden disease with a high impact on global health. Conventional
therapies have several drawbacks; thus, the development of effective therapies is required …
therapies have several drawbacks; thus, the development of effective therapies is required …
Toward biomaterials for enhancing immune checkpoint blockade therapy
Despite the remarkable progress in immune checkpoint blockade (ICB) therapy for cancer
treatment, low objective response and immune‐related side effects (immune‐related …
treatment, low objective response and immune‐related side effects (immune‐related …
Targeted cancer immunotherapy: nanoformulation engineering and clinical translation
M Yu, W Yang, W Yue, Y Chen - Advanced Science, 2022 - Wiley Online Library
With the rapid growth of advanced nanoengineering strategies, there are great implications
for therapeutic immunostimulators formulated in nanomaterials to combat cancer. It is crucial …
for therapeutic immunostimulators formulated in nanomaterials to combat cancer. It is crucial …
T-cell engaging poly (lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing …
Bispecific nanoparticles (NPs) are conjugated with two antibodies that enhance T cell
cytotoxicity by sequentially targeting CD3 and tumor-specific proteins. This interaction …
cytotoxicity by sequentially targeting CD3 and tumor-specific proteins. This interaction …
Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy
C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …
Chronic inflammation's transformation to cancer: a nanotherapeutic paradigm
The body's normal immune response against any invading pathogen that causes infection in
the body results in inflammation. The sudden transformation in inflammation leads to the rise …
the body results in inflammation. The sudden transformation in inflammation leads to the rise …
Sonodynamical reversion of immunosuppressive microenvironment in prostate cancer via engineered exosomes
D Wang, Z Wan, Q Yang, J Chen, Y Liu, F Lu… - Drug delivery, 2022 - Taylor & Francis
Prostate cancer (PCa) responds poorly to routine immunotherapy due to the tumor
immunosuppressive microenvironment. Here, we describe an ultrasound-based drug …
immunosuppressive microenvironment. Here, we describe an ultrasound-based drug …
Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
Y Yang, H Li, C Fotopoulou, P Cunnea… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy
AE Metzloff, MS Padilla, N Gong… - Advanced …, 2024 - Wiley Online Library
Chimeric antigen receptor (CAR) T cell therapy has achieved remarkable clinical success in
the treatment of hematological malignancies. However, producing these bespoke cancer …
the treatment of hematological malignancies. However, producing these bespoke cancer …