Immunotherapy, in particular immune checkpoint blockade (ICB) therapy targeting the
programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) axis, has …

T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

Cancer immunotherapy is a groundbreaking strategy that has revolutionized the field of
oncology compared to other therapeutic strategies, such as surgery, chemotherapy, or …

Current advances of immunotherapy have greatly changed the way of cancer treatment. At
the same time, a great number of nanoparticle-based cancer immunotherapies (NBCIs) …

The treatment of malignancies has undergone dramatic changes in the past few decades.
Advances in drug delivery techniques and nanotechnology have allowed for new …

Simple Summary Cancer becomes one of the major public health problems globally and the
burden is expected to be increasing. Currently, both the medical and research communities …

It is currently understood that in order for a tumor to successfully grow, it must evolve means
of evading immune surveillance. In the past several decades, researchers have leveraged …

Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …

Recently, magnetic nanoparticles (MNPs) have more and more often been used in
experimental studies on cancer treatments, which have become one of the biggest …

T-cell-based immunotherapy, such as CAR-T cells and bispecific T-cell engagers (BiTEs),
has shown promising clinical outcomes in many cancers; however, these therapies have …