Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage,
such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 …

While there is general agreement on the necessity to measure glomerular filtration rate
(GFR) in many clinical situations, there is less agreement on the best method to achieve this …

Background Increased mortality risk is associated with short-term temperature variability.
However, to our knowledge, there has been no comprehensive assessment of the …

Background Population mean GFR is lower in older age, but it is unknown whether healthy
aging is associated with preserved rather than lower GFR in some individuals. Methods We …

Introduction Kidney function declines with age, but its determinants in the general population
remain incompletely understood. We investigated the rate and determinants of kidney …

In the last decades, improvements in the average life expectancy in the world population
have been associated with a significant increase in the proportion of elderly people, in …

Chemotherapy-induced nausea and vomiting (CINV) are still two of the most feared side
effects of cancer therapy. Although major progress in the prophylaxis of CINV has been …

Chronic kidney disease (CKD) has a prevalence of approximately 13% and is most
frequently caused by diabetes and hypertension. In population studies, CKD etiology is often …

Rapid age-related glomerular filtration rate (GFR) decline increases the risk of end-stage
renal disease, and a low GFR increases the risk of mortality and cardiovascular disease …