[HTML][HTML] Xenobiotics shape the physiology and gene expression of the active human gut microbiome

CF Maurice, HJ Haiser, PJ Turnbaugh - Cell, 2013 - cell.com
The human gut contains trillions of microorganisms that influence our health by metabolizing
xenobiotics, including host-targeted drugs and antibiotics. Recent efforts have characterized …

General principles of antibiotic resistance in bacteria

JL Martinez - Drug Discovery Today: Technologies, 2014 - Elsevier
Highlights•Environmental microorganisms are the origin of antibiotic resistance genes
acquired by human pathogens through HGT.•The use of antibiotics has selected a small …

Surveying membrane landscapes: a new look at the bacterial cell surface

T Lithgow, CJ Stubenrauch, MPH Stumpf - Nature Reviews Microbiology, 2023 - nature.com
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …

Biology of antimicrobial resistance and approaches to combat it

SM Schrader, J Vaubourgeix, C Nathan - Science translational …, 2020 - science.org
Insufficient development of new antibiotics and the rising resistance of bacteria to those that
we have are putting the world at risk of losing the most widely curative class of medicines …

Mechanisms of antimicrobial resistance in Stenotrophomonas maltophilia: a review of current knowledge

T Gil-Gil, JL Martínez, P Blanco - Expert Review of Anti-infective …, 2020 - Taylor & Francis
Introduction: Stenotrophomonas maltophilia is a prototype of bacteria intrinsically resistant to
antibiotics. The reduced susceptibility of this microorganism to antimicrobials mainly relies …

Emergence and spread of antibiotic resistance: setting a parameter space

JL Martínez, F Baquero - Upsala journal of medical sciences, 2014 - Taylor & Francis
The emergence and spread of antibiotic resistance among human pathogens is a relevant
problem for human health and one of the few evolution processes amenable to experimental …

Pathogenic and indigenous denitrifying bacteria are transcriptionally active and key multi-antibiotic-resistant players in wastewater treatment plants

L Yuan, Y Wang, L Zhang, A Palomo… - Environmental …, 2021 - ACS Publications
The global rise and spread of antibiotic resistance greatly challenge the treatment of
bacterial infections. Wastewater treatment plants (WWTPs) harbor and discharge antibiotic …

Versatile polymer-based strategies for antibacterial drug delivery systems and antibacterial coatings

K You, B Gao, M Wang, X Wang, KC Okoro… - Journal of Materials …, 2022 - pubs.rsc.org
Human health damage and economic losses due to bacterial infections are very serious
issues worldwide. Excessive use of antibiotics has caused an increase in bacterial …

[HTML][HTML] Unraveling antimicrobial resistance using metabolomics

M Kok, L Maton, M van der Peet, T Hankemeier… - Drug Discovery …, 2022 - Elsevier
The emergence of antimicrobial resistance (AMR) in bacterial pathogens represents a
global health threat. The metabolic state of bacteria is associated with a range of genetic …

[HTML][HTML] Food and human gut as reservoirs of transferable antibiotic resistance encoding genes

JM Rolain - Frontiers in microbiology, 2013 - frontiersin.org
The increase and spread of antibiotic resistance (AR) over the past decade in human
pathogens has become a worldwide health concern. Recent genomic and metagenomic …