Multidrug efflux pumps are chromosomally encoded genetic elements capable of mediating
resistance to toxic compounds in several life forms. In bacteria, these elements are involved …

Antibiotics have natural functions, mostly involving cell-to-cell signaling networks. The
anthropogenic production of antibiotics, and its release in the microbiosphere results in a …

One of the challenges in clinical infectious diseases is the problem of chronic infections,
which can require long durations of antibiotic treatment and often recur. An emerging …

The aquatic environment may represent an essential route for transmission of antibiotic
resistance to opportunistic human pathogens. Since industrial wastewater is discharged into …

The development of antibiotic resistance is usually associated with genetic changes, either
to the acquisition of resistance genes, or to mutations in elements relevant for the activity of …

The cell envelope is essential for survival and adaptation of bacteria. Bacterial membrane
proteins include the major porins that mediate the influx of nutrients and several classes of …

Tackling antibiotic resistance necessitates deep understanding of how resource competition
within and between species modulates the fitness of resistant microbes. Recent advances in …

Intrinsically resistant bacteria have emerged as a relevant health problem in the last years.
Those bacterial species, several of them with an environmental origin, present naturally low …

Dry-fermented sausages are meat products highly valued by many consumers.
Manufacturing process involves fermentation driven by natural microbiota or intentionally …

Metabolism is deeply intertwined with aging. Effects of metabolic interventions on aging
have been explained with intracellular metabolism, growth control, and signaling. Studying …