The analysis of the genomes of bacterial pathogens indicates that they have acquired their
pathogenic capability by incorporating different genetic elements through horizontal gene …

For many bacterial infections, noninherited mechanisms of resistance are responsible for
extending the term of treatment and in some cases precluding its success. Among the most …

The gut microbiota is a repository of antibiotic resistance genes (ARGs), which may affect the
health of humans and animals. The intestinal flora is affected by many factors but it is …

A photoactive manganese nitrosyl, namely [Mn (PaPy3)(NO)](ClO4)({Mn-NO}), has been
loaded into the columnar pores of an MCM-41 host. Strong interaction between the polar …

Fluoroquinolones (FQs) are important antibiotics used for treatment of Salmonella infection
in poultry in many countries. However, oral administration of fluoroquinolones may affect the …

Bacterial growth and metabolic rates are often closely related. However, under antibiotic
selection, a paradox in this relationship arises: antibiotic efficacy decreases when bacteria …

Metabolic adaptations accompanying the development of antibiotic resistance in bacteria
remain poorly understood. To study this relationship, we profiled the growth of lab-evolved …

The anaerobic, gastrointestinal pathogen Clostridioides difficile can cause severe forms of
enterocolitis which is mainly mediated by the toxins it produces. The RNA polymerase …

Background: Traditionally, infections are treated with antimicrobials (for example, antibiotics,
antiseptics, etc), but antimicrobial resistance (AMR) has become one of the most serious …

To achieve robust replication, bacteria must integrate cellular metabolism and cell wall
growth. While these two processes have been well characterized, the nature and extent of …