Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …

Bacteria–phage coevolution, the reciprocal evolution between bacterial hosts and the
phages that infect them, is an important driver of ecological and evolutionary processes in …

The rise of multi-drug-resistant (MDR) bacteria has spurred renewed interest in the use of
bacteriophages in therapy. However, mechanisms contributing to phage-mediated bacterial …

Bacteria and their viral predators (bacteriophages) are locked in a constant battle. In order to
proliferate in phage-rich environments, bacteria have an impressive arsenal of defence …

In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

The rise of antibiotic-resistant bacterial strains, causing intractable infections, has resulted in
an increased interest in phage therapy. Phage therapy preceded antibiotic treatment against …

Bacteria-phage symbioses are ubiquitous in nature and serve as valuable biological
models. Historically, the ecology and evolution of bacteria-phage systems have been …

When we think about viruses we tend to consider ones that afflict humans—such as those
that cause influenza, HIV, and Ebola. Yet, vastly more viruses infect single-celled microbes …

Antibiotic resistance evolution in bacteria indicates that one of the challenges faced by
phage therapy is that, sooner or later, bacteria will evolve resistance to phages. Evidently …

Phage therapy has been viewed as a potential treatment for bacterial infections for over a
century. Yet, the year 2016 marks one of the first phase I/II human trials of a phage …