Low‐carbohydrate diets: nutritional and physiological aspects

A Adam‐Perrot, P Clifton, F Brouns - Obesity reviews, 2006 - Wiley Online Library
Recently, diets low in carbohydrate content have become a matter of international attention
because of the WHO recommendations to reduce the overall consumption of sugars and …

Colorectal cancer: molecular mutations and polymorphisms

AS Sameer - Frontiers in oncology, 2013 - frontiersin.org
Colorectal cancer (CRC) is one of the major causes of mortality and morbidity, and is the
third most common cancer in men and the second most common cancer in women …

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

G Cuevas-Ramos, CR Petit, I Marcq… - Proceedings of the …, 2010 - National Acad Sciences
Escherichia coli is a normal inhabitant of the human gut. However, E. coli strains of
phylogenetic group B2 harbor a genomic island called “pks” that codes for the production of …

Socioeconomic status and the risk of colorectal cancer: an analysis of more than a half million adults in the National Institutes of Health‐AARP Diet and Health Study

CA Doubeni, AO Laiyemo, JM Major, M Schootman… - Cancer, 2012 - Wiley Online Library
BACKGROUND: No previous prospective US study has examined whether the incidence of
colorectal cancer (CRC) is disproportionately high in low socioeconomic status (SES) …

Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM–p53 cascade in colon cancer cell lines

L Fini, E Hotchkiss, V Fogliano, G Graziani… - …, 2008 - academic.oup.com
The Mediterranean diet is rich in extra virgin olive oil (EVOO) and associated with a lower
incidence of colorectal cancer. EVOO contains phenolic extracts with potential …

Animal origin foods and colorectal cancer risk: a report from the Shanghai Women's Health Study

SA Lee, XO Shu, G Yang, H Li, YT Gao… - Nutrition and …, 2009 - Taylor & Francis
The association of animal-origin food consumption and cooking patterns with colorectal
cancer (CRC) risk was evaluated in a cohort of 73,224 participants of the Shanghai …

Fundamental flaws of hormesis for public health decisions

KA Thayer, R Melnick, K Burns… - Environmental Health …, 2005 - ehp.niehs.nih.gov
Hormesis (defined operationally as low-dose stimulation, high-dose inhibition) is often used
to promote the notion that while high-level exposures to toxic chemicals could be detrimental …

A functional role for Smad7 in sustaining colon cancer cell growth and survival

C Stolfi, V De Simone, A Colantoni, E Franze… - Cell death & …, 2014 - nature.com
Initially identified as an inhibitor of transforming growth factor (TGF)-β mainly owing to its
ability to bind TGF-β receptor type I and abrogate TGF-β-driven signaling, Smad7 can …

Safety and efficacy of high-protein diets for weight loss

AM Johnstone - Proceedings of the Nutrition Society, 2012 - cambridge.org
Dietary strategies that can help reduce hunger and promote fullness are beneficial for
weight control, since these are major limiting factors for success. High-protein (HP) diets …

Loss of AP-2α results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo

B Schwartz, VO Melnikova, C Tellez, A Mourad-Zeidan… - Oncogene, 2007 - nature.com
Abstract Activator protein-2 (AP-2) is a transcription factor that regulates proliferation and
differentiation in mammalian cells and has been implicated in the acquisition of the …