[HTML][HTML] Plant phenolics: Bioavailability as a key determinant of their potential health-promoting applications

P Cosme, AB Rodríguez, J Espino, M Garrido - Antioxidants, 2020 - mdpi.com
Phenolic compounds are secondary metabolites widely spread throughout the plant
kingdom that can be categorized as flavonoids and non-flavonoids. Interest in phenolic …

[HTML][HTML] Neuroprotective effects of quercetin in Alzheimer's disease

H Khan, H Ullah, M Aschner, WS Cheang, EK Akkol - Biomolecules, 2019 - mdpi.com
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. It is widely distributed among plants and found commonly in daily diets …

Rutin as a potent antioxidant: Implications for neurodegenerative disorders

AB Enogieru, W Haylett, DC Hiss… - Oxidative medicine …, 2018 - Wiley Online Library
A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Mechanisms of neuroprotection by quercetin: counteracting oxidative stress and more

LG Costa, JM Garrick, PJ Roquè… - Oxidative medicine and …, 2016 - Wiley Online Library
Increasing interest has recently focused on determining whether several natural
compounds, collectively referred to as nutraceuticals, may exert neuroprotective actions in …

[HTML][HTML] Multi-modality machine learning predicting Parkinson's disease

MB Makarious, HL Leonard, D Vitale, H Iwaki… - npj Parkinson's …, 2022 - nature.com
Personalized medicine promises individualized disease prediction and treatment. The
convergence of machine learning (ML) and available multimodal data is key moving …

Quercetin and the mitochondria: a mechanistic view

MR de Oliveira, SM Nabavi, N Braidy, WN Setzer… - Biotechnology …, 2016 - Elsevier
Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits
and vegetables. It has been traditionally viewed as a potent antioxidant and anti …

[HTML][HTML] Flavonoids as a natural enhancer of neuroplasticity—An overview of the mechanism of neurorestorative action

N Cichon, J Saluk-Bijak, L Gorniak, L Przyslo, M Bijak - Antioxidants, 2020 - mdpi.com
Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …

Protective mechanisms of flavonoids in Parkinson's disease

KB Magalingam, AK Radhakrishnan… - Oxidative medicine …, 2015 - Wiley Online Library
Parkinson's disease is a chronic, debilitating neurodegenerative movement disorder
characterized by progressive degeneration of dopaminergic neurons in the substantia nigra …

[HTML][HTML] Quercetin: a bioactive compound imparting cardiovascular and neuroprotective benefits: scope for exploring fresh produce, their wastes, and by-products

IUH Bhat, R Bhat - Biology, 2021 - mdpi.com
Simple Summary The present review summarizes the generated hypothesis and critical role
of quercetin in cardiovascular and neuroprotective diseases reported over the last decade …

Rutin as neuroprotective agent: From bench to bedside

B Budzynska, C Faggio, M Kruk-Slomka… - Current medicinal …, 2019 - ingentaconnect.com
Flavonoids are major dietary constituents of plant-based food found ubiquitously in plant
kingdom where they are usually present in substantial amounts. Rutin is a flavonol-type …