Endogenous neurosteroids and synthetic neuroactive steroids (NAS) are important targets
for therapeutic development in neuropsychiatric disorders. These steroids modulate major …

The liver performs a multitude of bodily functions, whilst retaining the ability to regenerate
damaged tissue. In this review, we discuss sex steroid biology, regulation of mammalian …

Sex hormones and genes on the sex chromosomes are not only key factors in the regulation
of sexual differentiation and reproduction but they are also deeply involved in brain …

Alzheimer's disease (AD), a leading cause of dementia, has been a global concern. AD is
associated with the involvement of the central nervous system that causes the characteristic …

The postmenopausal state covers 40% of modern women's lives and 50–70% of
postmenopausal women report GSM symptoms such as vaginal dryness, itching, frequent …

Phytoestrogens are non-steroidal plant compounds, which bind to α and β estrogen
receptors, thereby causing specific effects. The best-known group of phytoestrogens are …

Osteoporosis is a significant concern in bone health, and understanding its
pathomechanism is crucial for developing effective prevention and treatment strategies. This …

The aim of this review is to appraise the data from available randomized clinical trials (RCT)
regarding the possible combinations of neuroleptic and non-antipsychotic treatment which …

Canine-mammary-gland tumors (CMTs) are prevalent in female dogs, with approximately
50% of them being malignant and often presenting as inoperable owing to their size or …

Breast cancer is the most diagnosed type of cancer amongst women in economically
developing countries and globally. Most breast cancers express estrogen receptor alpha …