Antioxidant dimethyl fumarate temporarily but not chronically improves intracortical microelectrode performance

GF Hoeferlin, T Bajwa, H Olivares, J Zhang… - Micromachines, 2023 - mdpi.com
Intracortical microelectrode arrays (MEAs) can be used in a range of applications, from basic
neuroscience research to providing an intimate interface with the brain as part of a brain …

Reactive Amine Functionalized Microelectrode Arrays Provide Short-Term Benefit but Long-Term Detriment to In Vivo Recording Performance

BS Sturgill, AG Hernandez-Reynoso… - ACS Applied Bio …, 2024 - ACS Publications
Intracortical microelectrode arrays (MEAs) are used for recording neural signals. However,
indwelling devices result in chronic neuroinflammation, which leads to decreased recording …

[HTML][HTML] Bacteria Invade the Brain Following Sterile Intracortical Microelectrode Implantation

J Capadona, G Hoeferlin, S Grabinski… - Research …, 2024 - ncbi.nlm.nih.gov
Brain-machine interface performance is largely affected by the neuroinflammatory
responses resulting in large part from blood-brain barrier (BBB) damage following …

Antioxidant Strategies to Mitigate the Neuroinflammatory Response to Intracortical Microelectrode Implantation

PE Boucher - 2024 - rave.ohiolink.edu
Chronic functionality of intracortical microelectrodes are limited by biological failure modes.
One common cause of these failures is the persistent presence of reactive oxygen species …