Lopinavir is a novel protease inhibitor (PI) developed from ritonavir. Coadministration with
low-dose ritonavir significantly improves the pharmacokinetic properties and hence the …

OBJECTIVES: This article reviews the clinical manifestations of mitochondrial toxicity
associated with the use of nucleoside analog reverse transcriptase inhibitors (NRTIs) and …

Highly active anti-retroviral therapies, which incorporate HIV protease inhibitors, resolve
many AIDS-defining illnesses. However, patients receiving protease inhibitors develop a …

Continually maintaining maximally suppressive drug concentrations represents a key
defence against the emergence of resistance. If drug levels fall and replication occurs, the …

We assessed the impact of an efavirenz-containing regimen versus a protease inhibitor-
containing regimen on quality of life, emotional status, and adherence of HIV-1-infected …

Abacavir is a carbocyclic 2′-deoxyguanosine nucleoside analogue. It is metabolised
intracellularly to a 2′-deoxyguanosine nucleoside analogue which competitively inhibits …

Delavirdine | Drugs Skip to main content SpringerLink Account Menu Find a journal Publish
with us Track your research Search Cart 1.Home 2.Drugs 3.Article Delavirdine A Review of its …

The authors examined factors associated with four dimensions of functional quality of life
(physical functioning, energy/fatigue, social functioning, and role functioning) in 142 men …

Nelfinavir | Drugs Skip to main content SpringerLink Account Menu Find a journal Publish with
us Track your research Search Cart 1.Home 2.Drugs 3.Article Nelfinavir An Update on its Use …

Objective: To compare continuous highly active antiretroviral therapy with a CD4 cell count-
driven structured treatment interruption (STI) strategy. The primary end-point was the …