[HTML][HTML] Recent progress and challenges in the development of antisense therapies for myotonic dystrophy type 1
T De Serres-Bérard, S Ait Benichou, D Jauvin… - International journal of …, 2022 - mdpi.com
Myotonic dystrophy type 1 (DM1) is a dominant genetic disease in which the expansion of
long CTG trinucleotides in the 3′ UTR of the myotonic dystrophy protein kinase (DMPK) …
long CTG trinucleotides in the 3′ UTR of the myotonic dystrophy protein kinase (DMPK) …
[HTML][HTML] Comprehensive Cardiovascular Management of Myotonic Dystrophy Type 1 Patients: A Report from the Italian Neuro-Cardiology Network
Myotonic dystrophy is a hereditary disorder with systemic involvement. The Italian Neuro-
Cardiology Network-“Rete delle Neurocardiologie”(INCN-RNC) is a unique collaborative …
Cardiology Network-“Rete delle Neurocardiologie”(INCN-RNC) is a unique collaborative …
Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy
Myotonic dystrophy (DM) is caused by expansions of C (C) TG repeats in the non-coding
regions of the DMPK and CNBP genes, and DM patients often suffer from sudden cardiac …
regions of the DMPK and CNBP genes, and DM patients often suffer from sudden cardiac …
[HTML][HTML] Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels
Myotonic dystrophy type 1 (DM1) is a genetic disorder that causes muscle weakness and
myotonia. In DM1 patients, cardiac electrical manifestations include conduction defects and …
myotonia. In DM1 patients, cardiac electrical manifestations include conduction defects and …
[HTML][HTML] Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1
VKM Ginjupalli, M Cupelli, JB Reisqs… - Frontiers in …, 2023 - frontiersin.org
Introduction: Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by
the increased number of CTG repeats in 3′ UTR of Dystrophia Myotonia Protein Kinase …
the increased number of CTG repeats in 3′ UTR of Dystrophia Myotonia Protein Kinase …
[HTML][HTML] Myotonic Dystrophy: From Molecular Pathogenesis to Therapeutics
L Timchenko - International Journal of Molecular Sciences, 2022 - mdpi.com
Current studies concerning myotonic dystrophy type 1 (DM1) are in the process of
transitioning from molecular investigations to preclinical and clinical trials. Several papers …
transitioning from molecular investigations to preclinical and clinical trials. Several papers …
[HTML][HTML] Prevalence of Steinert's Myotonic Dystrophy and Utilization of Healthcare Services: A Population-Based Cross-Sectional Study
L Hernáez, AC Zoni, MF Domínguez-Berjón… - Healthcare, 2024 - mdpi.com
Myotonic dystrophy type I (MDI) is the most common muscular dystrophy in adults. The main
objectives of this study were to determine the prevalence of MDI in the Community of Madrid …
objectives of this study were to determine the prevalence of MDI in the Community of Madrid …
[HTML][HTML] Natural history of cardiac involvement in myotonic dystrophy type 1–Emphasis on the need for lifelong follow-up
H Petri, BJY Mohammad, AT Kristensen… - International Journal of …, 2024 - Elsevier
Background Cardiac involvement represents a major cause of morbidity and mortality in
patients with myotonic dystrophy type 1 (DM1) and prevention of sudden cardiac death …
patients with myotonic dystrophy type 1 (DM1) and prevention of sudden cardiac death …
[HTML][HTML] Case report: A rare complication after the implantation of a cardiac implantable electronic device: Contralateral pneumothorax with pneumopericardium and …
Cardiac implantable electronic devices (CIED) including pacemakers (PM), implantable
cardioverter defibrillators (ICD), and cardiac resynchronized therapy (CRT) have become …
cardioverter defibrillators (ICD), and cardiac resynchronized therapy (CRT) have become …
[HTML][HTML] Evaluation of index of cardiac electrophysiological balance in patients with myotonic dystrophy type 1
Background: Myotonic dystrophy type 1 (MD1), which is characterized by decreased muscle
tone, progressive muscle weakness, and cardiac involvement, is an autosomal dominant …
tone, progressive muscle weakness, and cardiac involvement, is an autosomal dominant …