Ketamine has rapid yet often transient antidepressant effects in patients with treatment-
resistant depression. Different strategies have been proposed to prolong these effects …

Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …

Ketamine is an effective intervention for treatment-resistant depression (TRD), including late-
in-life (LL-TRD). The proposed mechanism of antidepressant effects of ketamine is a …

Abstract Ammonium ion (NH4+) is the major suspected molecule responsible for
neurological complications of hepatic encephalopathy (HE). No specific pharmacological …

Ketamine has shown antidepressant effects in patients with major depressive disorder
(MDD) resistant to first‐line treatments and approved for use in this patient population …

A single subanesthetic infusion of ketamine can rapidly alleviate symptoms of treatment-
resistant major depression. Since repeated administration is required to sustain symptom …

Depression is a leading cause of disability globally, with a prevalence of 3.8% among the
whole population, 5% of the adult population, and 5.7% of the elderly population over 60 …

Background Subanesthetic ketamine infusions can elicit rapid and sustained antidepressant
effects, yet the potential cognitive impact of ketamine has not been thoroughly examined …

Numerous emotional and cognitive processes mediated by the hippocampus present
differences between sexes and can be markedly influenced by hormonal status in males …

Introduction Racemic ketamine, a derivative of phencyclidine, has been used as a
dissociative anesthetic since 1970. In 2000, the first randomized controlled trial showed a …