[HTML][HTML] New insights into natural products that target the gut microbiota: Effects on the prevention and treatment of colorectal cancer

L Lu, J Dong, Y Liu, Y Qian, G Zhang, W Zhou… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

[HTML][HTML] Metabolic reprogramming of colorectal cancer cells and the microenvironment: implication for therapy

M Nenkov, Y Ma, N Gaßler, Y Chen - International journal of molecular …, 2021 - mdpi.com
Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

[HTML][HTML] Gut microbiota-derived metabolites in colorectal cancer: the bad and the challenges

W Zhang, Y An, X Qin, X Wu, X Wang, H Hou… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence from studies in humans and animal models has elucidated that gut
microbiota, acting as a complex ecosystem, contributes critically to colorectal cancer (CRC) …

[HTML][HTML] The cytokine network in colorectal cancer: Implications for new treatment strategies

H Braumüller, B Mauerer, J Andris, C Berlin, T Wieder… - Cells, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only
limited therapeutic options. CRC is not only a genetic disease with several mutations in …

[HTML][HTML] Reprogramming of Treg cells in the inflammatory microenvironment during immunotherapy: a literature review

X Wu, Z Zhou, Q Cao, Y Chen, J Gong… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Treg), as members of CD4+ T cells, have garnered extensive attention in
the research of tumor progression. Treg cells have the function of inhibiting the immune …

[HTML][HTML] Microbiota of the gastrointestinal tract: Friend or foe?

MA Senchukova - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
The gut microbiota is currently considered an external organ of the human body that
provides important mechanisms of metabolic regulation and protection. The gut microbiota …

[HTML][HTML] Mechanism and strategies of immunotherapy resistance in colorectal cancer

J Shan, D Han, C Shen, Q Lei, Y Zhang - Frontiers in immunology, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer in the world. Although there are
standard treatment options for CRC, most patients respond poorly to these treatments …

[HTML][HTML] Gut microbiota-derived short-chain fatty acids regulate gastrointestinal tumor immunity: a novel therapeutic strategy?

Y Dong, K Zhang, J Wei, Y Ding, X Wang… - Frontiers in …, 2023 - frontiersin.org
Tumor immune microenvironment (TIME), a tumor-derived immune component, is proven to
be closely related to the development, metastasis, and recurrence of tumors. Gut microbiota …

[HTML][HTML] Interaction between microbiota and immunity and its implication in colorectal cancer

C Xing, Y Du, T Duan, K Nim, J Chu, HY Wang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world.
Besides genetic causes, colonic inflammation is one of the major risk factors for CRC …

[HTML][HTML] Modulation of the tumor Microenvironment by Microbiota-derived short-chain fatty acids: impact in colorectal cancer therapy

S Gomes, AC Rodrigues, V Pazienza… - International Journal of …, 2023 - mdpi.com
Finding new therapeutic approaches towards colorectal cancer (CRC) is of increased
relevance, as CRC is one of the most common cancers worldwide. CRC standard therapy …