[HTML][HTML] Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

[HTML][HTML] The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

[HTML][HTML] Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

[HTML][HTML] Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer

Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …

[HTML][HTML] Mesenchymal stem/stromal cells in cancer therapy

T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

Non-viral vectors for RNA delivery

Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Engineered extracellular vesicles and their mimetics for cancer immunotherapy

C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …

Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis

Z He, J Wang, C Zhu, J Xu, P Chen, X Jiang, Y Chen… - Cancer Letters, 2022 - Elsevier
Inflammatory molecules and exosomes are crucial for signal transduction between tumor-
associated macrophages and tumor cells. IL-6, a key inflammatory molecule secreted by M2 …

[HTML][HTML] TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p …

Z Yu, Y Wen, N Jiang, Z Li, J Guan, Y Zhang, C Deng… - Biomaterials, 2022 - Elsevier
Retinal ischemia-reperfusion injury (IRI) is one of the main pathogenic mechanisms of
glaucoma, which are largely unknown, including neuroinflammation and neuronal death in …

[HTML][HTML] Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications

A Amiri, R Bagherifar, E Ansari Dezfouli… - Journal of Translational …, 2022 - Springer
Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …