Next generation gold drugs and probes: chemistry and biomedical applications

RT Mertens, S Gukathasan, AS Arojojoye… - Chemical …, 2023 - ACS Publications
The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Unraveling ligand exchange reactions in linear neutral Au (i) and Cu (i) N-heterocyclic carbene complexes for biological applications

GC Rodrigues, MVF Barrionuevo… - New Journal of …, 2024 - pubs.rsc.org
Linear complexes of the form [M (NHC) Cl](M= Au (I) or Cu (I), NHC= N-heterocyclic
carbene) are promising drug candidates due to their potent in vitro antitumor, antibacterial …

Evaluation of Gold Complexes to Address Bacterial Resistance, Quorum Sensing, Biofilm Formation, and Their Antiviral Properties against Bacteriophages

A Marques, SAC Carabineiro, M Aureliano, L Faleiro - Toxics, 2023 - mdpi.com
The worldwide increase in antibiotic resistance poses a significant challenge, and
researchers are diligently seeking new drugs to combat infections and prevent bacterial …

Heteroleptic (S^ C)-cyclometallated gold (III) complexes as novel antiviral agents

M Balsera-Manzanero, RG Soengas… - Heliyon, 2024 - cell.com
Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in
healthy individuals and the associated high morbidity in immunosuppressed patients …

[PDF][PDF] REAÇÕES DE TROCA DE LIGANTES DE CANDIDATOS A METALOFÁRMACOS [AU (IMES) CL] E [CU (IMES) CL] ESTUDADAS POR MÉTODOS …

GC Rodrigues, MVF Barrionuevo, MA San-Miguel… - reunioes.sbpcnet.org.br
Metalofármacos de M (I), M= Au (I) e Cu (I) são promissores para o tratamento de várias
doenças, como os de Au (I) para tratamento de artrite reumatóide. Nosso grupo estuda …