Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly
correlates with clinical disease activity and epithelial injury in inflammatory bowel disease …

Patients with active inflammatory bowel disease (IBD) have elevated and activated myeloid
leucocytes which infiltrate the colonic mucosa in vast numbers. Myeloid leucocytes such as …

BACKGROUND: Generalized pustular psoriasis (GPP) is a chronic autoimmune disease
characterized by fever, erythema, and neutrophilic pustules over large areas of the skin …

Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly
correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current …

Pyoderma gangrenosum (PG) is a rare, neutrophilic skin disease. For the purpose of
accurate diagnosis and proper treatment of PG, the Japanese clinical practice guidance for …

Ulcerative colitis and Crohn's disease are the major phenotypes of the idiopathic
inflammatory bowel disease (IBD), which afflicts millions of individuals throughout the world …

Inflammatory and/or autoimmune diseases like ulcerative colitis (UC) or Crohn's disease
(CD) are debilitating chronic disorders that poorly respond to pharmacological interventions …

Introduction Inflammatory bowel disease (IBD) is a chronic immune-mediated disease of the
gastrointestinal tract comprising Crohn's disease (CD) and ulcerative colitis (UC). While any …

BACKGROUND/AIM: The Adacolumn selectively depletes granulocytes and monocytes/
macrophages, which are thought to be part of the immunopathogenesis of ulcerative colitis …

The inference that granulocytes and monocytes/macrophages (GM) are part of the
immunopathogenesis of inflammatory bowel disease (IBD) and hence should be targets of …