Endoglin (CD105) is a type-1 integral transmembrane glycoprotein and coreceptor for
transforming growth factor-β (TGF-β) ligands. The endoglin/TGF-β signaling pathway …

Endoglin (CD 105, TGF-β receptor III) is a homodimeric transmembrane glycoprotein that
plays a regulatory role in TGF-β signaling. Its functional role in the context of atherosclerosis …

Following arterial occlusion, blood vessels respond by forming a new network of functional
capillaries (angiogenesis), by reorganizing preexisting capillaries through the recruitment of …

Abstract Purpose of Review The loss of contractile function after heart injury remains one of
the major healthcare issues of our time. One strategy to deal with this problem would be to …

Hereditary hemorrhagic telangiectasia (HHT) is a potentially life-threatening genetic
vascular disorder caused by loss-of-function mutations in the genes encoding activin …

Increased soluble endoglin (sENG) has been observed in human brain arteriovenous
malformations (bAVMs). In addition, the overexpression of sENG in concurrence with …

Endoglin (CD105) is a type III auxiliary receptor for the transforming growth factor beta
(TGFβ) superfamily. Several lines of evidence suggest that endoglin plays a critical role in …

The diagnosis of pulmonary arterial hypertension (PAH) is frequently delayed. We
hypothesized that circulating angiogenic modulatory protein levels might correspond with …

Rationale: The pathogenesis of bicuspid aortic valve (BAV)–associated aortopathy is poorly
understood, and no prognostic biomarker is currently available. Objective: We aimed to …

Preeclampsia is a pregnancy-specific disease of high prevalence characterized by the onset
of hypertension, among other maternal or fetal signs. Its etiopathogenesis remains elusive …