[HTML][HTML] Distinct effects of calorie restriction on adipose tissue cytokine and angiogenesis profiles in obese and lean mice
E Kurki, J Shi, E Martonen, P Finckenberg… - Nutrition & …, 2012 - Springer
Background Obesity associates with low-grade inflammation and adipose tissue
remodeling. Using sensitive high-throughput protein arrays we here investigated adipose …
remodeling. Using sensitive high-throughput protein arrays we here investigated adipose …
TGFβ signaling and congenital heart disease: Insights from mouse studies
HM Arthur, SD Bamforth - … Defects Research Part A: Clinical and …, 2011 - Wiley Online Library
Transforming growth factor β (TGFβ) regulates one of the major signaling pathways that
control tissue morphogenesis. In vitro experiments using heart explants indicated the …
control tissue morphogenesis. In vitro experiments using heart explants indicated the …
[HTML][HTML] L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction
B Oujo, JM Munoz-Felix, M Arevalo, E Nunez-Gomez… - PLoS …, 2014 - journals.plos.org
Transforming growth factor-β (TGF-β) plays a pivotal role in renal fibrosis. Endoglin, a 180
KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of …
KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of …
High levels of soluble endoglin induce a proinflammatory and oxidative-stress phenotype associated with preserved NO-dependent vasodilatation in aortas from mice …
K Jezkova, J Rathouska, I Nemeckova… - Journal of vascular …, 2016 - karger.com
Aims: A soluble form of endoglin (sEng) was proposed to participate in the induction of
endothelial dysfunction in small blood vessels. Here, we tested the hypothesis that high …
endothelial dysfunction in small blood vessels. Here, we tested the hypothesis that high …
[HTML][HTML] The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations
Brain arteriovenous malformations (bAVMs) are focal vascular lesions composed of
abnormal vascular channels without an intervening capillary network. As a result, high …
abnormal vascular channels without an intervening capillary network. As a result, high …
The complex regulation of TGF-β in cardiovascular disease
S Redondo, J Navarro-Dorado, M Ramajo… - Vascular health and …, 2012 - Taylor & Francis
Transforming growth factor β (TGF-β1) is a pleiotropic cytokine with many and complex
effects in cell and tissue physiology. This is made possible by a very complex and …
effects in cell and tissue physiology. This is made possible by a very complex and …
[PDF][PDF] Atorvastatin-induced endothelial nitric oxide synthase expression in endothelial cells is mediated by endoglin
L Zemankova, M Varejckova, E Dolezalova… - J Physiol …, 2015 - jpp.krakow.pl
Endoglin, a transforming growth factor β (TGF-β) receptor type III, is co-expressed with
endothelial nitric oxide synthase (eNOS) in aortic endothelium in atherosclerotic plaques of …
endothelial nitric oxide synthase (eNOS) in aortic endothelium in atherosclerotic plaques of …
[HTML][HTML] Stem cell-derived vessels-on-chip for cardiovascular disease modeling
M Marder, C Remmert, JA Perschel, M Otgonbayar… - Cell Reports, 2024 - cell.com
The metabolic syndrome is accompanied by vascular complications. Human in vitro disease
models are hence required to better understand vascular dysfunctions and guide clinical …
models are hence required to better understand vascular dysfunctions and guide clinical …
Cholesterol effects on endoglin and its downstream pathways in ApoE/LDLR double knockout mice
Z Strasky, L Vecerova, J Rathouska, M Slanarova… - Circulation …, 2011 - jstage.jst.go.jp
Background: The aim of the study was to evaluate whether cholesterol-rich diet affects
transforming growth factor-β-RIII (endoglin) levels in blood and 2 endoglin-related pathways …
transforming growth factor-β-RIII (endoglin) levels in blood and 2 endoglin-related pathways …
[HTML][HTML] High soluble endoglin levels do not induce endothelial dysfunction in mouse aorta
I Nemeckova, A Serwadczak, B Oujo, K Jezkova… - PLoS …, 2015 - journals.plos.org
Increased levels of a soluble form of endoglin (sEng) circulating in plasma have been
detected in various pathological conditions related to cardiovascular system. High …
detected in various pathological conditions related to cardiovascular system. High …